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VX710 & TAXOL--EFFECT IN WOMEN W/ ADV BREAST CANCER REFRACTORY TO TAXOL

VX710 & TAXOL--EFFECT IN WOMEN W/ ADV BREAST CANCER REFRACTORY TO TAXOL
VX710
批准号：
6263735
负责人：
CHRISTY RUSSELL
金额：
$3.56万
依托单位：
UNIVERSITY OF SOUTHERN CALIFORNIA
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6263735
关键词：
breast neoplasms clinical research combination chemotherapy drug resistance drug screening /evaluation female human subject human therapy evaluation immunomodulators neoplasm /cancer chemotherapy paclitaxel pharmacokinetics

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中文摘要
翻译
这项研究的目标是建立VX-710与紫杉醇联合使用的能力，以克服紫杉醇治疗后有进展性疾病记录的晚期乳腺癌妇女的临床耐药性。这项研究将确定VX-710的安全性和紫杉醇联合使用时的药代动力学。
英文摘要
The study objectives are to establish the ability of VX-710 given in combination with paclitaxel, to overcome clinical drug resistance in women with advanced breast carcinoma who have had documented progressive disease following treatment with paclitaxel. The study will establish the safety of VX-710 and the pharmacokinetics of paclitaxel when used in combination.
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会议论文
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