SERUM AND URINE GONADOTROPINS IN SEX STEROIDS IN NORMALLY CYCLING WOMEN

作为准备全国妇女大型多中心研究(SWAN)的一项试点可行性研究，该方案将记录血清促性腺激素卵泡刺激素(FSH)和黄体生成素(LH)水平以及性腺类固醇雌二醇和孕酮水平与尿液FSH、LH水平以及类固醇代谢物戊二醇葡糖醛酸苷和雌酮葡萄糖醛酸苷之间的相关性。这项可行性研究将在7个临床地点招募35名妇女。预计尿液和血清水平之间的良好相关性将被注意到，为更大的亲本方案中计划的尿路研究做准备。

As a pilot feasibility study in preparation for the large multi-center Study of Women Across the National (SWAN), this protocol will document the correlation between serum levels of the gonadotropins follicle stimulating hormone (FSH) and lutinizing hormone (LH) and the gonadal steroids estradiol and progesterone with urinary levels of FSH, LH and the steroid metabolites pergnanediol glucuronide and estrone glucuronide. A total of 35 women will be recruited at 7 clinical sites for this feasibility study. It is anticipated that good correlation between urinary and serum levels will be noted in preparation for the planned urinary studies in the larger parent protocol.