DEVELOPMENTAL DETERMINANTS OF UPPER AIRWAY COLLAPSIBILITY

这项研究计划将有助于阐明 儿童OSAS通过确定解剖和 神经肌肉因素 更好地理解病理生理学 这种疾病将导致更好的管理和治疗， 最终使我们能够确定哪些患有OSAS的儿童处于危险之中， 在成年期复发的风险 早期识别 高风险患者将允许早期识别和治疗， 可能预防OSAS的复发。 受试者将接受 基线多导睡眠图，以确认他们正常或患有OSAS (this将作为OSAS临床评价的一部分进行 科目

This research proposal will help elucidate the pathophysiology of childhood OSAS by determining the relative roles of anatomic & neuromuscular factors. A better understanding of the pathophysiology of this disease will lead to better management & treatment, & may ultimately allow us to determine which children with OSAS are at risk for recurrence of the disease during adulthood. Early identification of high risk patients will allow for early recognition & treatment, & possibly prevention, of a recurrence of OSAS. Subjects will undergo baseline polysomnography to confirm that they are normal or have OSAS (this will have been done as part of the clinical evaluation in the OSAS subjects.