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INSULIN RESISTANCE AND GLUCOSE METABOLISM IN PREGNANCY

INSULIN RESISTANCE AND GLUCOSE METABOLISM IN PREGNANCY
妊娠期胰岛素抵抗和葡萄糖代谢
批准号:
6115353
负责人:
Patrick Catalano
金额:
$1.92万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30

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中文摘要
翻译
本研究的长期目标是从系统和细胞水平了解妊娠期母体脂代谢与母体代谢适应的关系。 该建议的具体目的是:评价母体胰岛素敏感性的纵向变化,因为它与葡萄糖耐量正常和妊娠糖尿病的瘦和肥胖妇女的母体脂质代谢和脂肪积累有关;评价妊娠晚期母体脂质代谢的变化与新生儿身体成分的关系;并确定在正常糖耐量和妊娠糖尿病的妊娠晚期脂肪组织中胰岛素敏感性降低的细胞机制。
英文摘要
The long term objectives are to understand the relationship of pregravid maternal lipid metabolism and maternal metabolic adaptations during pregnancy at the system and cellular level. The specific aims of this proposal are to : evaluate the longitudinal changes in maternal insulin sensitivity as it relates to maternal lipid metabolism and fat accretion in lean and obese women with normal glucose tolerance and gestational diabetes; evaluate the alterations in maternal lipid metabolism in late pregnancy in relationship to neonatal body composition; and, identify the cellular mechanisms underlying decreased insulin sensitivity in adipose tissue during late gestation in normal glucose tolerance and gestational diabetes.
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Impact of a Postpartum Lifestyle Intervention on Lactation outcomes, Breastmilk Composition and Infant Growth
  • 批准号:
    10427595
  • 项目类别:
  • 资助金额:
    $26.52万
  • 财政年份:
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  • 负责人:
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  • 依托单位:
Impact of a Postpartum Lifestyle Intervention on Lactation outcomes, Breastmilk Composition and Infant Growth
  • 批准号:
    10707041
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Lifestyle Intervention in Preparation for Pregnancy (LIPP)
  • 批准号:
    10302258
  • 项目类别:
  • 资助金额:
    $53.19万
  • 财政年份:
    2018
  • 负责人:
    Patrick Catalano
  • 依托单位:
Lifestyle Intervention in Preparation for Pregnancy (LIPP)
  • 批准号:
    9849601
  • 项目类别:
  • 资助金额:
    $69.68万
  • 财政年份:
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  • 负责人:
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