课题基金 / 基金详情

SAFETY AND EFFICACY OF GROWTH HORMONE FROM ADOLESCENCE TO ADULTHOOD

SAFETY AND EFFICACY OF GROWTH HORMONE FROM ADOLESCENCE TO ADULTHOOD
从青春期到成年生长激素的安全性和有效性
批准号：
6297766
负责人：
MITCHELL GEFFNER
金额：
$0.19万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
1998
资助国家：
美国
项目状态：
已结题
起止时间：
1998-12-01 至 1999-11-30
来源：
https://reporter.nih.gov/project-details/6297766
关键词：
body composition child (0-11) clinical research drug metabolism drug screening /evaluation hormone therapy human subject human therapy evaluation longitudinal human study pediatric pharmacology peptide hormone metabolism pituitary dwarfism placebos somatotropin

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中文摘要
翻译
这项研究将允许记录代谢状态和身体 儿童期发作（CO）GH缺乏（GHD）患者的组成 对刺激性GH刺激无反应，首先在他们的时间， 生长激素治疗通常会停止第二次根据他们的 治疗GH或安慰剂超过两年的时间，第三， 与假定的GHD患者比较发现，在GH 停止，是GH-足够的基础上挑衅GH测试。
英文摘要
This study will allow documentation of the metabolic status and body composition of childhood-onset (CO) GH-deficient (GHD) patients unresponsive to provocative GH stimulation, firstly at the time their GH therapy would ordinarily be stopped secondly accoring to their treatment with GH or placebo over a two-year period, and thirdly in comparison with presumed GHD patients found, at the time of GH cessation, to be GH-sufficient based on provocative GH testing.
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