NEW TRITIUM LABELLING REAGENTS & TECHNIQUES SYNTHESIS REVIEW ARTICLE

一篇评论文章正在为《合成》杂志准备 有机化学（合成）. 本次审查将提出一个调查， 新型高比活度氚标记试剂， 国家氚标记设施开发的技术，以及 它们在氚标记化学中的应用。 审查将 根据试剂的类型，其发展和 一些应用程序。 重点将放在试剂和 合成能力极高的技术 高比活度氚标记化合物。 的焦点 这篇评论将是关于化学标记合成，它不会 包括氢-氚交换反应或生物化学方法。 本文目前的规划表明，它将包含六个 具体如下：1. 导言2. 合成及应用 氚化氚3. 氚化试剂的合成及应用 水4. 用氚气进行多相催化氚化5。 氚标记通过有机化合物6. 结论7. 希望这一审查将于2005年年底完成。 1999年夏天

A review article is in preparation for the journal Synthetic Organic Chemistry (Synthesis). This review will present a survey of the new high specific activity tritium labelling reagents and techniques developed at the National Tritium Labelling Facility, and their applications to tritium labelling chemistry. The review will be organized on the basis of the type of reagent, its development and some applications. Emphasis will be placed on the reagents and techniques that have exceptionally high capability for the synthesis of high specific activity tritium labelled compounds. The focus of this review will be on chemical labelling synthesis, and it will not include hydrogen-tritium exchange reactions or biochemical methods. Current planning for this article suggests it will contain six sections as follows: 1. Introduction 2. Synthesis and Applications of Tritiated Tritides 3. Synthesis and Applications of Tritiated Water 4. Heterogeneous Catalytic Tritiation with Tritium Gas 5. Tritium Labelling via Organometallic Compounds 6. Conclusion 7. References It is hoped that this review will be complete by the end of Summer 1999.