BODY REPRESENTATIONS--NEUROPSYCHOLOGY AND ANATOMIC BASIS

描述：(改编自申请人摘要)建议的 调查的目的是促进目前有限的理解 关于大脑表达的本质和解剖学基础 人体。这些表征包括身体意象、身体图式和 车身结构描述。一组未被选中的受试者 单侧中风将在一系列任务中进行测试，以确定 躯体表象障碍的患病率及其解剖学定义 这些影响的基础是通过将表现与病变部位联系起来 由神经成像研究定义。那些表现出 涉及特定类型的身体表征的损害将作为 旨在定义身体的第二系列研究中的受试者 陈述将作为第二系列研究的对象 在定义这些影响的基础上的机制。一系列 将进行调查以评估可能的治疗作用。 以身体模式为目标的干预措施。最后，一系列 将使用功能磁共振成像对正常人进行调查，以调查 假定的身体表象的解剖学基础。 拟议的研究既有临床研究也有理论研究。 意义。从理论上讲，这些研究将提供 对身体认知结构的重要见解 申述。这项工作的潜在临床意义也是 安全。如果正如假设的那样，身体模式对行动至关重要， 针对这一陈述的干预可能具有重要的意义 治疗方面的影响。

DESCRIPTION: (Adapted From The Applicant's Abstract) The proposed investigations are intended to advance the currently limited understanding of the nature and anatomic bases of the brain's representations of the human body. These representations include the body image, body schema and body structural description. An unselected group of subjects with unilateral stroke will be tested on a battery of tasks to determine the prevalence of disorders of body representation and to define the anatomic bases of these effects by correlating performances with lesion site as defined by neuro-imaging studies. Those patients who demonstrate impairments involving specific types of body representations will serve as subjects in a second series of studies aimed at defining of body representations will serve as subjects in a second series of studies aimed at defining the mechanisms that underlie these effects. A series of investigations will be performed to assess the possible therapeutic role of interventions targeting the body schema. Finally, a series of investigations in normals using fMRI will be performed to investigate the anatomic underpinnings of the postulated body representations. The proposed investigations have both clinical and theoretical significance. From a theoretical standpoint, these studies would offer important insights into the cognitive architecture of body representations. The potential clinical significance of this work is also clear. If, as hypothesized, the body schema is crucial to action, interventions targeting this representations may have important therapeutic implications.