MICROWAVE THERMOKERATOPLASTY WITH SURFACE COOLING

描述（改编自申请人的摘要）：本发明的目的是为了描述本发明。 研究的目的是设计和构建一个系统的临床版本， 表面冷却微波热角膜成形术 近视，并评估这种治疗的屈光效果， 动物实验一年后 具体而言，申请人建议 改善本项目第一阶段测试的系统， 减少治疗所需的技术技能的特征。 此外，提出了测试的假设，两个指定 角膜中治疗环的直径将产生稳定的、指定的 一年后的屈光变化。 微波热角膜成形术 使角膜的基质层在光学膜周围形成一个环， 区域通过吸收微波能量，以改变 角膜的曲率，因此其屈光力。 拟议 系统结合了表面冷却，以保护上皮免受 高温 因此，无需等待 治疗后再上皮化，如目前的情况， 放射状角膜切开术和屈光性角膜切除术等技术。 该设备具有巨大的商业潜力，因为大约 50%的美国人需要矫正视力。 拟议商业应用：不可用

DESCRIPTION (Adapted from Applicant's Abstract): The objectives of this research are to design and construct a clinical version of a system for microwave thermokeratoplasty with surface cooling for correction of myopia, and to assess the refractive effects of such treatments in animal subjects after one year. Specifically, the applicants proposed to improve the system tested in Phase I of this project by adding features that reduce the technical skill required to treat. Furthermore, the proposed to test the hypothesis that two specified diameters of treated ring in the cornea would produce stable, specified changes in refraction after one year. Microwave thermokeratoplasty shrinks the stromal layer of the cornea in a ring around the optical zone through absorption of microwave energy in order to change the curvature of the cornea and hence its dioptric power. The proposed system incorporates surface cooling to protect the epithelium from elevated temperatures. Consequently, there is no need to wait for re-epithelialization after treatment, as is the case with current techniques, such as radial keratotomy and photorefractive keratectomy. There is significant commercial potential for this device, since roughly 50% of the U.S. population requires correction to vision. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE