GORDON RESEARCH CONFERENCE ON REPRODUCTIVE TRACT BIOLOGY

本申请要求为将于2000年7月2日至7日举行的生殖道生物学戈登会议提供部分资金。请注意，由于会议的科学内容，我们要求国家儿童健康和人类发展研究所作为会议的主要赞助商。我们还请求由妇女健康办公室、国家癌症研究所、国家糖尿病、消化和肾脏疾病研究所、国家环境健康科学研究所和国家普通医学科学研究所联合发起。被要求赞助的人数反映了这次会议的不同寻常之处，它侧重于男性和女性生殖道器官和器官系统的生物学和病理学，而不是特定的分子或过程。因此，这次会议吸引了来自从基础科学到临床实践的各种领域和背景的与会者。因此，本次会议的主要目标是促进关于生殖道的跨学科交流和信息整合。三个具体目标将使我们能够实现这一目标：第一，会议的科学内容将达到最高水平。为了达到这一卓越标准，我们邀请在各自领域具有国际公认的前沿专家的演讲者。有一个有趣的组合，既有多年来在各自领域处于领先地位的知名研究人员，也有其他领域同样知名的研究人员，他们对转基因小鼠的表型分析揭示了这些分子在生殖道中意想不到的新奇行为。其次，对与重要临床问题高度相关并有可能转化为医疗实践的研究有强烈的重视。例如，一整堂课的重点是乳腺中荷尔蒙信号的机制，特别强调导致乳腺癌的异常。第三，非常强调纳入学生和初级同事，因为任何领域的未来都取决于下一代调查人员。总而言之，我们计划了一次激动人心的会议，这符合生殖道生物学戈登会议的丰富传统，该会议已经存在了近30年。我们预计，新的地点(康涅狄格州新伦敦康涅狄格州学院)以及与哺乳动物配子发生和胚胎发生会议永久会面的意向将提高本次会议的质量，与会者一直给予该会议极高的评价。

This application requests partial funding for the Reproductive Tract Biology Gordon Conference to be held July 2-7, 2000. Please note that due to the scientific content of the meeting we request the National Institute of Child Health and Human Development as the primary sponsor of the meeting. We also request joint sponsorship by the Office of Women's Health, the National Cancer Institute, National Institute of Diabetes, Digestive and Kidney Diseases, the National Institute for Environmental Health Sciences, and the National Institute of General Medical Sciences. The number of requested sponsors reflects the unusual nature of this conference which focuses on the biology and the pathology of the organs and organ systems of the male and female reproductive tracts, rather than on specific molecules or processes. Therefore, this meeting attracts participants from a wide variety of fields and backgrounds ranging from basic science to clinical practice. Accordingly, the principal goal of this conference is to stimulate cross- disciplinary exchange and integration of information concerning the reproductive tract. Three specific aims will allow us to accomplish this goal: First, the scientific content of the meeting will be at the highest level. To achieve this standard of excellence, we are inviting speakers who are internationally recognized experts at the forefront of their fields. There is an interesting blend of established investigators who have been leaders in their respective areas for many years and equally renowned researchers in other fields whose phenotypic analyses of transgenic mice have uncovered unexpected and novel actions of these molecules in the reproductive tract. Second, there is a strong emphasis on research that is highly relevant to important clinical questions and has potential for translation into medical practice. For example, one entire session focuses on mechanisms of hormonal signaling in the context of the mammary gland with a special emphasis on aberrations that lead to breast cancer. Third, there is a strong emphasis on the inclusion of students and junior colleagues because the future of any field depends on the next generation of investigators. In summary, we have planned an exciting meeting that is in accord with the rich traditions of the Reproductive Tract Biology Gordon Conference, which has been in existence for nearly 30 years. We envision that the new site (Connecticut College, New London Connecticut) and the intent to meet on a permanent basis with the Mammalian Gametogenesis and Embryogenesis Conference will enhance the quality of this meeting, which has consistently been rated extremely high by the attendees.