TRAINING IN BIOTECHNOLOGY: EMPHASIS ON PROTEIN CHEMISTRY

此申请是为了续签1989年首次授予华盛顿州立大学的生物技术培训补助金，这是美国国立卫生研究院资助的博士预科项目的第一年。这项补助金已于1994年以竞争方式续期，我们现在申请下一个5年期的补助金。自从我们上次更新以来，我们的培训教师的突出地位得到了突出的荣誉，包括两次当选为国家科学院院士，我们的学员开创了一种成就的模式。我们的跨学科项目主要强调蛋白质化学，这是华盛顿州立大学的一个突出领域，对生物技术至关重要。来自四所学院（农业、工程、科学和兽医）六个学位授予单位的二十名教师在这一领域提供了深度和广度，并将作为实习生研究的导师。受训者参加的核心培训包括实验室轮转、课程、研讨会、期刊俱乐部、工业实习和生物技术专题讨论会。特别值得注意的是一门创新的生物技术课程，由学生小组围绕生物技术提案的发展组织，利用实验室轮转建立跨学科联系，以及一个受到热烈欢迎的实习计划。该项目在生物化学/生物物理学、化学工程、遗传学和细胞生物学、微生物学、植物生理学和兽医微生物学和病理学等学位课程的选择上具有很大的灵活性。每年将有五名新学员进入该项目。头两年的薪金支助将由培训补助金资金提供，并由机构资金补充，以后各年由机构资金提供，以后各年由导师可用的资金提供。在任何时候，大约有30名学生将参与培训。该机构坚定地致力于培训计划，并继续提供财政支持。培训学院在竞争性研究资助和培养高产杰出的科学家和工程师方面有着良好的记录。在最初的几年里，我们招收了各种各样的高素质学生，其中包括相当数量的妇女和少数民族。毕业的受训者在生物技术领域获得了博士后研究人员等具有竞争力的职位，并随后获得了长期职位。该计划提供与生物技术相关的最先进的基础科学培训和生物技术应用方面的教育，两者都强调蛋白质化学，从而培养具有良好跨学科背景的科学家和工程师，有资格满足生物技术的主要需求。

This application is for renewal of the Biotechnology Training Grant first awarded to Washington State University in 1989, the first year of the NIH-funded Predoctoral Program. The grant was competitively renewed in 1994 and we now apply for the next 5-year period. Since our previous renewal, the prominence of our training faculty has been highlighted by honors including two elections to the National Academy of Sciences and our trainees have initiated a pattern of achievement. Our cross- disciplinary program has a major emphasis on protein chemistry, an area of prominence at WSU and of central importance to biotechnology. Twenty- fix faculty from six degree-grant units in four Colleges (Agriculture, Engineering, Sciences and Veterinary Medicine) provide depth and breadth in this area and will serve as preceptors for trainee research. Trainees participate in a core of training involving laboratory rotations, courses, seminars, journal clubs, industrial internships and biotechnology symposia. Of particular note are an innovate biotechnology course organized around development of biotechnology proposals by groups of students, the use of laboratory rotations to establish interdisciplinary contact and an enthusiastically received internship program. The program has significant flexibility in options for degree programs among Biochemistry/Biophysics, Chemical Engineering, Genetics and Cell Biology, Microbiology, Plant Physiology, and Veterinary Microbiology and Pathology. Each year five new trainees will enter the program. Salary support will be provided for the first two years by Training Grant funds supplemented by institutional funds and for subsequent years by institutional funds and for subsequent years by funds available to preceptors. At any one time, approximately 30 students will be involved in training. The institution is strongly committed to the training program and continues to provide financial support. The training faculty has a strong record of competitive research funding and of training productive and prominent scientists and engineers. In the initial none years, we have enrolled a diverse group of high quality students including a significant number of women and minorities. Graduated trainees have taken competitive positions as postdoctoral researchers and subsequently long-term positions in biotechnology. The program provides state-of-the-art training in basic science relevant to biotechnology and an education in the applied aspects of biotechnology, both with an emphasis on protein chemistry, and thus produces scientists and engineers with sound interdisciplinary backgrounds, qualified to meet major needs of biotechnology.