COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY

本申请的目的是记录 华盛顿大学（UW）作为一个有效的和 在拟定的多中心临床试验中， 标题为“青光眼初始治疗合作研究”（CIGTS）。这 研究的目的是评估开角型青光眼的初始治疗是否 青光眼是更有效的手段，逐步，医疗方案或 手术方法。 华盛顿大学的临床中心将参加 在CIGTS中，通过识别和招募合格的患者， 给予CIGTS分配的治疗方案 协调中心，并在研究操作手册中定义， 随访和保留研究患者，记录和转移研究 数据到协调中心，并有助于报告，将 CIGTS的结果。 本申请描述了华盛顿大学临床中心的能力， 根据以下初步研究，每年入组约32例患者： 在3个月期间进行患者合格性研究。细节 提供我们的计划，以确定，招聘，遵循和保留这些 患者，我们的意图是获得一致的高质量数据， 治疗的视觉效果，以及可用的人员和设施 在我们的中心内执行CIGTS手册的规定， 运营

The intent of this application is to document the ability of the University of Washington (UW) to participate as an effective and productive clinical center in the proposed multicenter clinical trial, entitled, "Collaborative Initial Glaucoma Treatment Study" (CIGTS). This study's purpose is to evaluate whether initial treatment of open-angle glaucoma is more effective by means of a stepped, medical regimen or by means of a surgical approach. The UW's Clinical Center will participate in the CIGTS by identifying and recruiting eligible patients, administering the treatment regimen as assigned by the CIGTS's Coordinating Center and defined within the study's Manual of Operations, following and retaining study patients, recording and transferring study data to the Coordinating Center, and contributing to reports that will present the CIGTS results. This application describes the ability of the UW's Clinical Center to enroll approximately 32 patients per year, based upon pilot studies of patient eligibility conducted during a 3-month period. Details are provided of our plans to identify, recruit, follow, and retain these patients, our intent to obtain consistently high quality data on the visual outcomes of treatment, and the personnel and facilities available within our center to carry out the provisions of the CIGTS's Manual of Operations.