ESTABLISH OF POST CHERNOBYL NIS THYROID BANKS

描述：（申请人的描述） 该项目将形成一个国际支持的合作研究 资源为许多团体工作的问题，甲状腺癌， 切尔诺贝利事故之后。 它旨在促进合作， 避免在使用有限和非常宝贵的资源方面的竞争。 四 参与该项目的资助组织是国家研究所， 美国、欧盟委员会、世界卫生组织和 日本佐川纪念健康基金会 该项目的基础是 从甲状腺病例中收集组织的合作方法 切尔诺贝利周围地区的癌症，同时收集血液 样本和基本临床信息。 该项目有几个目标：（a） 确保向患者提供尽可能好的诊断服务，（B） 提供国际公认的病理学家同意的诊断。 这 将向这些国家的研究小组提供诊断结果 开展分子生物学、治疗学、流行病学和其他 问题研究 (c)以确保甲状腺癌的标本 描述和抽样，并提供适当的材料 研究（冷冻组织、固定组织切片、提取DNA/RNA和 血液样本，以及相关信息）， 相关的研究机构。 该项目将提供一个宝贵的 未来研究人员对辐射机制感兴趣的研究工具 放射后甲状腺的肿瘤发生。

DESCRIPTION: (Applicant's Description) This project will form an internationally supported collaborative research resource for many groups working on the problems of thyroid cancer which has followed the Chernobyl accident. It is designed to promote collaboration and avoid competition in the use of limited and very valued resources. The four funding organizations involved in the project are the National Institute of Health of the USA, the European Commission, the World Health Organization and the Sasakawa Memorial Health Foundation of Japan. The basis of the project is a collaborative approach to the collection of the tissue from cases of thyroid cancer in the areas around Chernobyl with simultaneous collection of blood samples and basic clinical information. The project has several aims (a) to ensure that the best possible diagnostic service is given to patients, (b) to provide a diagnosis agreed by internationally recognized pathologists. This diagnosis will be made available to research groups from those countries carrying out molecular biological, therapeutic, epidemiological and other studies. (c) to ensure that specimens of thyroid cancer are properly described and sampled, and that materials are available for appropriate research studies (frozen tissue, fixed tissue sections, extracted DNA/RNA and blood samples, together with relevant information), through a protocol agreed by the research organizations involved. The project will provide a valuable research tool for future researchers interested in the mechanism of radiation tumourigenesis of the thyroid following irradiation.