PROSTATE NEOPLASM--DEVELOPMENTAL PROJECTS

我们将继续我们的发展研究计划，包括 支持两个调查员发起的试点项目申请的指令 以及在特定领域的有针对性的研究，这些领域很可能 推进孢子的翻译研究目标。总预算 用于发展研究计划的资金将为20万美元，其中 大约75%将分配给试点项目资金，25%分配给 有针对性地开展研究。试点项目选择的优先事项 包括那些真正有创意、高度创新、属于 尽可能高的科学素质。这些项目也应该是补充 孢子的长期研究目标，并为成功做出贡献 我们的翻译研究目标。有针对性的研究优先事项 包括高度精选实验或临床计划，以解决 根据科学咨询机构的判断，我们的孢子计划中的具体需求 委员会审议阶段。 到目前为止，发展研究方案已被证明在 我们的孢子研究计划的增长和扩大，并已加速 朝着我们特定的翻译目标取得进展。通过Pilot 项目资金，才华横溢的高级调查人员一直 被招募专注于前列腺癌的转译研究。在……里面 此外，这一计划在招聘有前途的人方面发挥了重要作用 斯科特泌尿外科和贝勒的其他初级教员 各部门。在我们最初的孢子资助期间，试点项目获得了 已经被许多调查人员成功地转化为实质性的 同行评审的研究资助，在某些情况下，授予领导角色 在孢子内。 发展研究经费使用的审查机制，我们 在收到孢子资金后启动，取得了极大的成功。这个 在伯特·W·奥马利领导下的科学咨询委员会， 医学博士已经承担了评估、优先排序和授予 发展研究经费。我们将保持基本结构不变 该委员会也将继续由奥马利博士领导。 但由于不断增加的责任和复杂性 面对科学顾问委员会的决定，我们增加了两个 其他成员。我们对我们的功能非常乐观 发展研究计划，并预计它将继续发挥作用 是我们孢子成功的根本原因。

We will continue our Developmental Research Program which includes directives to support both investigator initiated pilot project application as well as targeted research in specific areas that are highly likely to advance the translational research goals of the SPORE. The total budget for the Developmental Research Program will be $200,000 of which approximately 75% will be allocated for pilot project funding and 25% for target research initiatives. Priorities for pilot project selection include those that are truly creative, highly innovative, and are of the highest possible scientific quality. These projects should also complement the long-term research goals of the SPORE and contribute toward the success of our translational research objectives. The targeted research priorities include highly select experimental or clinical initiatives that address a specific need in our SPORE program as judged by the Scientific Advisory Committee. The Developmental Research Program has thus far proved critical in the growth and expansion of our SPORE research program and has accelerated progress toward our specific translational objectives. Through pilot project funding, highly talented senior-level investigators have been recruited to focus on translational research in prostate cancer. In addition, this program has played an important role in recruiting promising junior-level faculty to the Scott Department of Urology and to other Baylor departments. During our initial SPORE-funding period, pilot project awards have been successfully converted by many investigators into substantial peer reviewed research grant awards, and in some cases, to a leading role within the SPORE. The review mechanism for use of Development Research Funds, which we initiated upon receiving SPORE funding, has been highly successful. The Scientific Advisory Committee, under the direction of Bert W. O'Malley, M.D. has assumed responsibility for evaluating, prioritizing, and awarding developmental research funding. We will maintain the basic structure of the committee, which will also remain under the direction of Dr. O'Malley. But because of the increasing responsibilities and complexity of the decisions facing of Scientific Advisory Committee, we have added two additional members. We are highly optimistic regarding the function of our Developmental Research Program and anticipate that it will continue to play a fundamental role in the success of our SPORE.