CWRU SPECTRAL KARYOTYPING SYSTEM

这是一个建议，以扩大分子细胞遗传学，位于凯斯西储大学遗传学系的Reinberger实验室内的数字成像设施。购买应用光谱成像“SkyVision”光谱成像系统和集成蔡司Axioplan 2显微镜将大大提高我们的荧光原位杂交（FISH）能力。它将允许研究人员在这所大学进行实验，我们目前无法做到的，并将有助于确保完成公共卫生服务资助的研究赠款金在CWRU这里。 这种最先进的仪器在分析荧光FISH检测中各种荧光染料的光谱特性方面具有独特的能力，并将补充现有的仪器。 新的成像系统将用于基础和临床研究目的。

This is a proposal to expand the digital imaging facility within the Reinberger Laboratories for Molecular Cytogenetics, located in the Department of Genetics at Case Western Reserve University. The purchase of an Applied Spectral Imaging "SkyVision" Spectral Imaging System and integrated Zeiss Axioplan 2 microscope will greatly enhance our capabilities for multicolor fluorescence in situ hybridization (FISH). It will allow researchers at this University to perform experiments that we are currently unable to do and will help ensure completion of PHS- funded research grants here at CWRU. This state-of-the-art instrument is unique in its capabilities to analyze the spectral properties of various fluorescent dyes in multicolor FISH assays and will complement existing instrumentation. The new imaging system will be used for both basic and clinical research purposes.