ELASTIC SCATTERED RAMAN SIGNAL IN IRRADIATED BLOOD SAMPLES

我们最近令人鼓舞的结果表明，近红外拉曼可以 测量全血中的分析物浓度， 让我们研究近红外光探测血液样本的方式。 两个特别重要的量是：a）特征 从照射的血液样品中出现的拉曼发射的直径 通过窄激光束;以及B）体积的特征深度 在这样的测量中被探测。 我们推导出了新的表达式， 让我们可以在电脑上计算这两个量， 样品的光学性质和直径的函数 激发光束 在接下来的研究中，我们将 实验数据的拉曼光斑尺寸，并比较它与 我们的模型表达式的预测。

With our recent encouraging results indicating that NIR Raman can measure analyte concentrations in whole blood, it becomes important for us to study the manner in which NIR light explores blood samples. Two particularly important quantities are: a) the characteristic diameter of the Raman emission emerging from a blood sample irradiated by a narrow laser beam; and b) the characteristic depth of the volume probed in such a measurement. We have derived new expressions that allow us to calculate both of these quantities on the computer as a function of the optical properties of the sample and the diameter of the excitation beam. In our upcoming studies, we will generate experimental data on Raman spot size and compare it with the predictions of our model expressions.