ORAL GLUCOSE TOLERANCE TEST & PREPARATORY DIET
ORAL GLUCOSE TOLERANCE TEST & PREPARATORY DIET
批准号:
6265656
负责人:
JOAN M MASTROBATTISTA
金额:
$1.11万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30
中文摘要
几十年来,每天给予含有150克碳水化合物的预备饮食,作为诊断妊娠期糖尿病的口服葡萄糖耐量试验(OGTT)的标准准备。 孕妇是否需要准备饮食还有待证实。 避免饮食将导致更简单的葡萄糖耐量试验管理。本研究的目的是确定是否准备饮食显着改变结果的葡萄糖耐量试验管理的孕妇。孕妇通常在妊娠24-28周之间进行1小时的葡萄糖挑战。 结果异常的妇女将组成研究组。 将在不准备饮食的情况下进行3小时口服葡萄糖耐量试验。 然后患者将接受标准高碳水化合物饮食3天。 将向受试者提供至少含有150 mg碳水化合物的食物,之后将重复葡萄糖耐量试验。 每名患者将作为自己的对照;将比较有和没有准备饮食的OGTT结果。 一项对20名患者的试点研究将首先进行测试。 根据这些结果,将计算样本量。
英文摘要
The administration of a preparatory diet containing 150 grams of carbohydrates/day for three days has been used for decades as a standard preparation for an oral glucose tolerance test (OGTT) for the diagnosis of gestational diabetes. The need for a preparatory diet in pregnant women needs to be confirmed. Avoiding the diet will result in simpler administration of the glucose tolerance test. The objective of this study is to determine whether a preparatory diet significantly alters the results of a glucose tolerance test administered to pregnant women. Pregnant women are routinely offered a 1-hour glucose challenge between 24-28 weeks gestation. Women with an abnormal result will compose the study group. A 3-hour oral glucose tolerance test will be administered without a preparatory diet. The patient will then be placed on a standard high carbohydrate diet for 3 days. Foods containing at least 150 mg of carbohydrate will be supplied to the participant, after which the glucose tolerance test will be repeated. Each patient will serve as her own control; the results of the OGTT with and without a preparatory diet will be compared. A pilot study of 20 patients will initially undergo testing. Based on these results, a sample size will be calculated.
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ORAL GLUCOSE TOLERANCE TEST & PREPARATORY DIET
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批准号:6309220
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项目类别:
-
资助金额:$1.11万
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财政年份:1999
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负责人:JOAN M MASTROBATTISTA
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依托单位: