STEROID HORMONES/MONOAMINE NEUROTRANSMITTERS IN PREMENSTRAL SYNDROME

月经黄体期的生理和情绪变化 经前综合症(PMS)在女性中很常见。经前综合症的原因不明， 可能与类固醇激素和 神经递质系统。卵巢类固醇激素与单胺 众所周知，神经递质在诊断中起着重要作用。 以及经前综合症的治疗。这个项目的主要目标是建立一个 卵巢类固醇激素水平与卵巢功能的相关性 经前综合征患者血浆中单胺类神经递质的变化及比较 与非经前综合征健康对照受试者比较。这项研究可能会导致 更好地了解经前综合症的病因，并有望改善 本综合征的诊断和治疗策略。量化的 将进行血浆中类固醇和神经递质的分析 采用气相色谱-质谱仪(GC/MS)进行分析。 将进行统计分析，以衡量显著相关性 在这些组件之间。血液样本将从 威廉姆斯医学诊所，霍莉·斯普林斯，两名本科生 来自铁锈学院的学生将有机会参加这次活动 通过实践经验进行研究项目。

Physical and emotional changes during the luteal phase of the menstrual cycle (PMS) are very common among women. The cause of PMS is unknown and may be related to interactions between steroid hormones and the neurotransmitter systems. The ovarian steroid hormones and the monoamine neurotransmitters are known to play a significant role in the diagnostic and treatment of PMS. The main goal of this project is to establish a correlation between the levels of the ovarian steroid hormones and the monamine neurotransmitters in the plasma of PMS patients and compare it to those of non-PMS healthy control subjects. This study may lead to better understanding the etiology of PMS and hopefully lead to improved diagnostic and treatment strategies for this syndrome. The quantitative analysis of steroids and neurotransmitters in plasma will be performed by the gas chromatography mass spectrometric technique (GC/MS). Statistical analysis will be made to measure significant correlation between these components. The blood samples will be obtained from the Williams Medical Clinic, Holly Springs, MS. Two undergraduate students from Rust College will have the opportunity to participate in this research project through hands-on experience.