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CLINICAL RESEARCH CENTER FOR STUDYING SENILE DEMENTIA

CLINICAL RESEARCH CENTER FOR STUDYING SENILE DEMENTIA
老年痴呆症临床研究中心
批准号:
2519714
负责人:
JEROME A YESAVAGE
金额:
$80.05万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-09-30 至 1998-08-31

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中文摘要
翻译
我们的老龄化临床研究中心(ACRC)的更新反映了 精神病学和行为学系的持续承诺 科学在斯坦福大学的研究阿尔茨海默氏症(AD)。 我们 中心重点关注与AD患者下降率相关的因素。 我们认为,研究诸如照顾者抑郁症的作用等问题, 睡眠障碍,以及其他医疗和精神问题, AD患者的总体下降可能导致治疗干预, 减少整体残疾、对机构护理和家庭的需求 艰苦创业 此外,我们认为,神经病理学,神经化学, 体内神经成像、神经心理学研究及其关系 下降率可以描述AD的亚型, 对病因学的见解。 这是一个“核心中心”,定义为中心 它主要提供核心研究功能,而不是直接 资助大型研究项目。 主要核心是: 1. 行政核心 2. 生物统计学/数据管理核心 3. 临床核心 4. 评估核心,检查临床核心的AD患者, 六个互补视角: 4a. 神经心理 4b. 神经影像学核心 4c. 睡眠核心 4便士 心理社会核心 4e. 神经化学核心 4楼 神经病理学核心
英文摘要
This renewal of our Aging Clinical Research Center (ACRC) reflects the continuing commitment of the Department of Psychiatry and Behavioral Sciences at Stanford to the study of Alzheimer's Disease (AD). Our Center focuses on factors associated with rate of decline in AD patients. We feel that examining issues such as the role of caregiver depression, sleep disorders, and other medical and psychiatric problems in the overall decline of AD patients may lead to treatment interventions that reduce overall disability, need for institutional care, and family hardship. Furthermore, we feel that neuropathological, neurochemical, in vivo neuroimaging, and neuropsychological studies and their relations to rate of decline could delineate subtypes of AD which could lead to insights into etiology. This is a "Core Center," defined as a Center that primarily provides Core research functions rather than directly funds large research projects. The main Cores are: 1. Administrative Core 2. Biostatistics/Data Management Core 3. Clinical Core 4. Assessment Cores, which examine the Clinical Core's AD patients from six complementary perspectives: 4a. Neuropsychology 4b. Neuroimaging Core 4c. Sleep Core 4d. Psychosocial Core 4e. Neurochemistry Core 4f. Neuropathology Core
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