COST EFFECTIVENESS OF MEDICAL NUTRITION THERAPY IN HYPERCHOLESTEROLEMIA

国家胆固醇教育计划（NCEP）将饮食疗法确定为高胆固醇血症的一线治疗。 NCEP指南建议医生和其他健康专业人员实施步骤1饮食，注册营养师（RD）实施步骤2饮食疗法。为了评估这种方法的有效性，研究人员随机分配了90名21-65岁的高胆固醇血症患者（60名男性，30名女性），他们没有接受降血脂药物，接受RD的医学营养治疗（MNT）或医生或护士的常规护理（UC）。 营养师使用基于NCEP的胆固醇降低方案提供MNT，该方案需要在6个月内进行2-6次访视，具体取决于脂质结果。 在6个月的干预期间，医生和患者同意不使用降胆固醇药物。使用控制基线和性别的协方差分析，比较治疗组之间较基线的变化。

The National Cholesterol Education Program (NCEP) identified diet therapy as the first line of treatment for hypercholesterolemia. NCEP guidelines suggest that a physician and other health professionals implement the Step 1 diet and that a registered dietitian (RD) implement Step 2 diet therapy. In order to evaluate the effectiveness of this approach, the investigators randomly assigned 90 patients (60 males, 30 females) aged 21-65 with hypercholesterolemia and not on hypolipidemic drugs to receive either medical nutrition therapy (MNT) from RDs or usual care (UC) from physicians or nurse practitioners. Dietitians provided MNT using a NCEP based cholesterol lowering protocol which required 2-6 visits over 6 months depending on lipid results. During the 6 month intervention period, physicians and patients agreed not to use cholesterol lowering drugs. Changes from baseline were compared between treatment groups using analysis of covariance controlling for baseline and gender.