ADOLESCENT SUBSTANCE ABUSE TREATMENT

手导疗法的最新发展和日益增长的 关于青少年亚群中的异质性的共识 精神活性物质使用障碍(PSUD)导致的 对患者-治疗匹配和临床研究的兴趣 手动指导疗法的发展。拟议的项目建立在 我们之前的研究集中在识别、表征、 以及治疗患有PSUD的青少年。这个项目的长期目标是 研究是为了检验表明治疗效果可以是 通过利用有特色的治疗方法显著改善 通过将患者与匹配的独特治疗方案相匹配 他们的需求。 将从部分地区招募至少300名青少年 为PSUD患者提供的住院计划(PHP) 为期12周的门诊-术后护理研究。在完成PHP后， 参与者将被随机分配到以下三种情况之一：a 最低限度的治疗维持组；认知-行为复发 预防(RP)组；或改进的动态(MD)互动组。 这项建议的具体目的是：1)审查是否 为PSUD完成PHP的青少年表现出更好的维护能力 在有时间限制的情况下继续提供成功的治疗结果 以RP或MD门诊团体干预的形式进行的后续护理 与那些只接受维持性善后治疗的人相比。 2)测试与以下相关的特定患者-治疗匹配假设 这些干预措施。

The recent development of manual guided therapies and the growing consensus regarding heterogeneity among subgroups of adolescents with psychoactive substance use disorders (PSUDs) has resulted in increased interest in clinical research on patient-treatment matching and development of manual guided therapies. The proposed project builds upon our previous studies that have focused on identifying, characterizing, and treating adolescents with PSUD. The long-term objectives of this study are to test hypotheses that suggest that treatment efficacy can be improved significantly by utilizing well characterized treatment methods and by matching patients to distinctive treatment regimen that match their needs. A minimum of 300 adolescents will be recruited from a Partial Hospitalization Program (PHP) for patients with PSUD and enrolled in a 12-week outpatient-aftercare study. Upon completion of the PHP, participants will be randomly assigned into one of three conditions: a minimal treatment maintenance group; a cognitive-behavioral relapse prevention (RP) group; or a modified dynamic (MD) interactional group. The specific aims of this proposal are: 1) To examine whether adolescents who complete PHP for PSUD demonstrate improved maintenance of successful treatment outcome when provided with time-limited continued aftercare in the form of RP or MD outpatient group intervention as compared with those who receive only maintenance aftercare treatment. 2) To test specific patient-treatment matching hypotheses related to these interventions.