Indoor/outdoor Bioaerosols Interface and Relationships Network - BioAirNet

2019年，英国公共卫生估计，在英国，每年有2.8万至3.6万人死于长期暴露在空气污染中。然而，我们仍然不知道生物来源的颗粒物(BioPM)或生物气溶胶在这种健康负担中扮演什么角色，也不知道暴露在室内或室外连续体中的确切影响。因此，我们还不知道如何控制BioPM。关于生物颗粒物排放的物理化学和生物特征如何在室内外连续体中受到影响，这些如何影响暴露模式，以及由此产生的健康影响，也存在着重大的知识差距。迄今缺乏进展的主要原因是科学学科和部门重点相互脱节，每个学科都有自己的视角、术语和方法。同样，缺乏关于剂量-反应关系的知识，以及人口在生命过程中以及在不同的室内和室外环境中对生物PM的易感性和心理社会、经济和身体脆弱性的变化情况，是估计健康惠益的关键障碍。因此，拟议的网络将解决量化和管理人类在从室内到室外的各种环境中接触生物颗粒物和相关健康风险所需的跨学科挑战。这项研究将与广泛的行为者接触，以实现社会影响，并建立交叉合作活动，以及全面的“生物暴露组”评估和特征的路线图。整个项目计划开展包括研讨会和在线讨论论坛在内的互动活动。这些活动将为参与者提供一个独特的机会，让他们在一个有争议的空间与不同的利益集团讨论围绕BioPM的问题。这将揭示围绕BioPM的政策和问题的新思维方式和创新解决方案，并告知该网络正在进行的重点。网络和传播活动包括一年一度的社区活动，展示创建一个连贯的研究社区所需的学科，该社区可以探索从分子一级的功能到引入新方法和技术的社会影响的所有领域。每个工作组(WG)都侧重于不同的主题，将确定优先领域，并吸收选定的参与者，以确保交叉受精和学科间的知识转让，将这些转化为利益攸关方、政策制定者和其他社区行为者的切实产出。与其他网络联合举办的活动将对相互交流和双向转让知识和专门知识起到重要作用。跨主题讲习班将作为跨学科和业界/学术讨论过渡性研究发展的沙坑。此外，还非常重视通过每年一次的早期职业研究人员会议、跨学科技能培训、外联活动、实验室间和行业间借调的积极方案以及直接分配的资金，增强早期职业研究人员(ECR)的能力，以便在国际活动中介绍工作。BioAirNet拥有强大而有力的管理和治理计划，有基于社区的利益相关者的高度参与，并努力吸引全球空中共同体的成员。

In 2019 the Public Health of England estimated that, in the UK, between 28,000 and 36,000 deaths a year can be attributed to long-term exposure to air pollution. However, we still do not know what role particulate matter of biological origins (BioPM) or bioaerosols play in this health burden nor the precise impact of exposures within the indoor or outdoor continuum. Therefore, we don't yet know how to control BioPM. There is also significant knowledge gap on how the physico-chemical and biological characteristics of BioPM emissions are affected at the indoor-outdoor continuum and how these affect exposure patterns and what are the resultant health impacts. The lack of progress to date mainly stems from disconnected scientific disciplines and sectoral foci, each with their own perspectives, terminology and methods. Likewise, lack of knowledge on dose-response relationships and changing landscapes of psychosocial, economical and physical vulnerability and susceptibility of the population to BioPM over the life course and in different indoor and outdoor environments are key barriers to the estimation of health benefits. Therefore, the proposed network will address the interdisciplinary challenge needed for quantifying and managing human exposure to biological particulate matters and related health risks across a continuum of diverse indoor to outdoor environments. The research will engage with a wide range of actors to realise societal impact and establish cross-collaboration activities along with a roadmap for a comprehensive "Bio-exposome" assessment and characterisation.Interactive activities including workshops and an online discussion forum are planned throughout the project. These activities will offer a unique opportunity for participants to debate issues around BioPM in a contested space with different interest groups. This will reveal new ways of thinking and innovative solutions to policy and issues around BioPM, as well as informing the ongoing focus of the network. Networking and dissemination activities include an annual based community event which showcases the disciplines needed to create a coherent research community that can explore the field all the way from functionality at a molecular level to the societal implications of introducing new approaches and technologies. Working groups (WG) each focused on a different theme will identify priority areas and draw on selected participants to ensure cross-fertilisation and the transfer of knowledge between disciplines, translating these into tangible outputs for stakeholders, policy-makers and other community-based actors. Joint events with other Networks will have an important function for cross-fertilisation and two-way transfer of knowledge and expertise. Cross-theme workshops will act as sandpits for cross-disciplinary and industry/academic discussion of transitional research developments. There is also a strong focus on empowering early career researchers (ECR) with an annual ECR conference, cross-disciplinary skills training, outreach activities, active programmes of inter-laboratory and industry secondments and directly allocated funds for ECR mobility to present work at international events.BioAirNet has a strong and robust management and governance plan that has a high level of community-based stakeholders' involvement and reaches out to attract membership of the Air Community worldwide.