CRC FOR THE STUDY OF SCHIZOPHRENIA & PSYCHIATRIC REHAB.

精神分裂症CRC是一个多学科组织， 进行诊断、评估和研究开发的科学家 和治疗方法，并提供核心研究服务， 独立供资的项目，包括心理生物学研究， 病因、病程和结局以及生物行为治疗对 精神分裂症和其他严重精神障碍。 一种启发式 能力-压力-保护因素概念框架 精神分裂症指导假设驱动的研究，作为回报， 了解项目结果。 纵向研究是多维的 在确定遗传，发育，神经认知， 社会行为、家庭和心理生理因素 精神病理学和心理社会功能。 CRC由核心实验室组成，提供直接和咨询服务。 为以下领域的综合和附属项目提供研究服务： 诊断/精神病理学，家庭过程， 认知/心理生理学/神经心理学，行为评估和 社会技能，精神药理学，方法学和统计学。 核心 实验室还进行仪器和试点的研究和开发 在有前途的领域的研究，导致独立的， 对新项目的校外支持。 《化学品审查公约》优先考虑制定和验证 创新和综合药物和心理社会治疗， 根据获得的知识设计的康复干预措施 通过研究，确定预测因素和相关因素， 精神分裂症的结果。 研究是有质量的 保证程序，保持严格、可靠和道德 通过全中心范围的、基于标准的培训来追求数据， 评估员、审计、同行协商和监测。 研究培训是与前和博士后和访问 临床研究员通过与CRC教师学徒。 在 在过去五年中，有50多名研究员在CRC接受了培训， 他们中的许多人在推出他们的 在其他地方的研究。 交叉验证、复制和 研究方法和新疗法的传播已经完成 通过与美国其他研究人员的合作研究， 和世界 促进采用和利用化学品审查委员会的调查结果 通过研讨会、出版物、手册， 和视频辅助治疗模块，以弥合研究之间的差距 和实践

The CRC for Schizophrenia is a multidisciplinary organization of scientists conducting research and development of diagnostic, assessment and treatment methods and providing core research services to independently funded projects comprising psychobiological studies of etiology, course and outcome and biobehavioral treatment effects on schizophrenia and other serious mental disorders. A heuristic vulnerability-stress-protective factors conceptual framework of schizophrenia guides hypothesis-driven research and, in return, is informed by project findings. Longitudinal studies are multidimensional in determining the interplay of genetic, developmental, neurocognitive, socio-behavioral, family, and psychophysiological factors on psychopathology and psychosocial functioning. The CRC consists of core labs that provide direct and consultative research services to integral and affiliated projects in areas of diagnosis/psychopathology, family processes, cognition/psychophysiology/neuropsychology, behavioral assessment and social skills, psychopharmacology, and methodology and statistics. Core labs also conduct research and development on instrumentation and pilot studies in promising areas, resulting in applications for independent, extramural support for new projects. Priority in the CRC is given to the development and validation of innovative and integrated drug and psychosocial treatment and rehabilitation interventions that are designed from knowledge gained through studies that identify predictors and correlates of course and outcome of schizophrenic disorders. Research is conducted with quality assurance procedures that maintain rigorous, reliable, and ethical pursuit of data through Center-wide, criterion-based training of assessors, audits, peer consultation, and monitoring. Research training is carried out with pre-and postdoctoral and visiting clinical research fellows through apprenticeships with CRC faculty. In the past five years, more than 50 fellows received training at the CRC, many of them continuing to collaborate with the CRC after launching their research careers elsewhere. Cross-validation, replication and dissemination of research methods and novel treatments is accomplished through collaborative studies with other investigators throughout the USA and the world. Adaptation and utilization of CRC findings are promoted among mental health clinicians through workshops, publications, manuals, and video-assisted treatment modules to bridge the gap between research and practice.