INTERCYCLE STUDY

这项研究的目的是加深我们对 患有特殊疾病的正常女性的生殖衰老过程 重点放在卵巢多肽上。卵泡的单向性增长 老年排卵期妇女的促性腺激素与正常 卵泡大小和明显正常的卵巢激素分泌。这些 老年女性的卵泡发育速度似乎加快了 随着急性卵泡雌二醇升高的更早开始， 促黄体生成素激增，排卵提前。这些发现是 表现为卵泡期缩短和总卵泡期缩短 月经周期长度。这项研究旨在进一步表征 这种通过抑制垂体而产生的促卵泡刺激素的变化 使用促性腺激素释放的所有受试者的促性腺激素分泌 激素激动剂，然后研究恢复反应后 停止镇压。

The goal of this study is to further our understanding of the reproductive aging process in the normal human female with special emphasis on the ovarian peptides. A monotropic rise in follicle stimulating hormone in older ovulatory women is associated with normal follicle size and apparently normal ovarian hormone secretion. These older women have what appears to be accelerated follicular development with earlier onset of the acute follicular estradiol rise, an earlier lutenizing hormone surge and earlier ovulation. These findings are manifested as a shortened follicular phase and a shortened total menstrual cycle length. This study is designed to further characterize this change in pituitary output of FSH by suppressing the pituitary gonadotropin secretion of all subjects using a gonadotropin releasing hormone agonist and then studying the recovery response after discontinued suppression.