课题基金 / 基金详情

CHEMOEMBOLIZATION AFTER CHEMOTHERAPY & RADIATION TREATMENT IN HEPATIC CANCER

CHEMOEMBOLIZATION AFTER CHEMOTHERAPY & RADIATION TREATMENT IN HEPATIC CANCER
化疗后化疗栓塞
批准号：
6274639
负责人：
CORNELIUS J MCGINN
金额：
$2.15万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6274639
关键词：
clinical research clinical trial phase I combination cancer therapy drug screening /evaluation embolism human subject human therapy evaluation leucovorin liver neoplasms mitomycin C neoplasm /cancer chemotherapy neoplasm /cancer radiation therapy pharmacokinetics

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中文摘要
翻译
这是一项丝裂霉素C在肝脏移植期间给药的I期试验。 化疗栓塞 这种治疗之前是肝动脉（HA） FUdR/甲酰四氢叶酸和全肝放射治疗。 本试验将 确定丝裂霉素C化疗栓塞的最大耐受剂量 全肝放疗联合单疗程HA后 化疗 缓解率和肝脏肿瘤的控制也将 进行评估。
英文摘要
This is a Phase I trial of mitomycin C given during hepatic chemoembolization. This treatment is preceded by hepatic artery (HA) FUdR/leucovorin and whole liver radiation therapy. This trial will determine the maximum tolerated dose of mitomycin C chemoembolization after whole liver radiation combined with a single course of HA chemotherapy. Response rate and the control of hepatic tumors will also be assessed.
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会议论文
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WHOLE LIVER RADIATION DOSE ESCALATION FOR INTRAHEPATIC CANCERS
LOW DOSE LIVER IRRADIATION WITH HEPATIC ARTERIAL CHEMOTHERAPY FOR CANCER
RADIATION DOSE ESCALATION FOR FOCAL LIVER CANCER
海外基金