PHARYNGEAL CARRIAGE RATE AND RESISTANCE PATTERN OF STREPTOCOCCUS IN HIV

本病例对照研究的流行殖民的 1996年12月开始在HIV感染儿童中使用肺炎球菌， 目前正在进行中。 这项研究的意义在于它将首次定义 预防血液感染的可能机制 肺炎双球菌复方新诺明预防无关 疾病PCP 它还将确定复方新诺明预防是否 影响了肺炎球菌的耐药模式，目前是一个主要的 疾病控制中心定义的新兴病原体。 在 此外，本研究开创了“PCRU-on-wheels”的概念。 的 PCRU工作人员正在4个诊所地点进行研究， PCRU中的中央处理和数据收集。

This case control study of the prevalence of colonization of the pneumococcus in HIV-infected children was begun on December, 1996 and is currently ongoing. This study will be significant inthat it will define for the first time possible mechanisms behind the protective effect against blood infection with pneumococci of cotrimoxazole prophylaxis against an unrelated disease, PCP. It will also define whether cotrimoxazole prophylaxis influences the resistance pattern of pneumococci, currently a major emerging pathogen as defined by the Centers for Disease Control. In addition, this study inaugurates the concept of "PCRU-on wheels". The study is being conducted by PCRU staff in 4 clinic locations, with central processing and data collection in the PCRU.