CHILD DEVELOPMENT IN RELATION TO EARLY OTITIS MEDIA

这项研究的主要目的是确定持续性中耳炎 在生命的前3年，渗出性介质(OME)会导致持久 言语、语言、认知或心理社会发展的障碍， 如果是这样的话，无论是通过及时鼓膜造口术来预防还是减轻- 管材放置(TTP)。来自2家医院和6家儿科诊所6391 好的，2个月大的婴儿入选。中耳状态和听力 被监视着。3岁以下，达到规定标准的儿童 永久性OME随机接受TTP，要么立即接受，要么在 定义的OME延长期持续存在。详细的开发测试如下 在3岁、4岁和6岁时给所有见过 随机化标准和代表光谱的其他样本 OME经验。对结果的分析将使确定 在早期OME和晚期发育障碍之间存在关联； 如果是，关联是否是因果关系；以及提示TTP是否是因果关系 有效地防止或减轻这种损害。

This study's main objectives are to determine whether persistent otitis media with effusion (OME) in the first 3 years of life results in lasting impairments of speech, language, cognitive, or psychosocial development, and if so, whether they are prevented or lessened by prompt tympanostomy- tube placement (TTP). From 2 hospitals and 6 pediatric practices 6391 well infants aged <2mo were enrolled. Middle-ear status and hearing are monitored. Up to age 3, children who reach specified criteria regarding persistent OME are randomized to undergo TTP either promptly or after a defined extended period of OME persists. Detailed developmental tests are administered at ages 3, 4 and 6 yr to all subjects who had met randomization criteria and to a sample of others representing a spectrum of OME experience. Analyses of results will enable determinations whether associations exist between early OME and later developmental impairments; if so, whether the associations are causal; and whether prompt TTP is effective in preventing or lessening such impairments.