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PILOT PHARMACOKINETIC STUDY TO EVALUATE D-TRANS MATRIX TESTOSTERONE

PILOT PHARMACOKINETIC STUDY TO EVALUATE D-TRANS MATRIX TESTOSTERONE
评估 D-Trans 基质睾酮的试点药代动力学研究
批准号：
6278180
负责人：
DAVID M COOK
金额：
$2.86万
依托单位：
OREGON HEALTH & SCIENCE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
项目状态：
已结题
起止时间：
1997-12-01 至 1998-11-30
来源：
https://reporter.nih.gov/project-details/6278180
关键词：
clinical research clinical trials hormone therapy human subject human therapy evaluation hypogonadism male pharmacokinetics testosterone transdermal drug delivery

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中文摘要
翻译
性腺功能减退（低睾酮）男性的睾酮替代疗法 是维持骨骼结构、力量、耐力和性能力所必需的 驱动 这种激素传统上以注射形式给予。 目前正在开发较新的药物输送形式。 本研究采用 性腺功能减退的男性来测试新的 一种称为D-TRANS Matrix Tetrase的开发皮肤贴剂 由Alza Corporation制造的制剂。
英文摘要
Testosterone replacement therapy for hypogonadal (low testosterone) males is necessary to maintain bone structure, strength, stamina and sexual drive. This hormone has traditionally been given in injection form. Newer drug delivery forms are currently being developed. This study uses hypogonadal males to test the safety and effectiveness of a newly developed skin patch referred to as D-TRANS Matrix Testosterone Formulations made by Alza Corporation.
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PILOT PHARMACOKINETIC STUDY TO EVALUATE D-TRANS MATRIX TESTOSTERONE
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EFFECT OF CHRONIC ALCOHOL USE ON THE HYPOTHALAMIC-PITUITARY-ADRENAL AXIS
CORTISOL INFUSION TEST TO DISTINGUISH BETWEEN ECTOPIC FROM PITUITARY EXCESS ACTH
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