A7: COMPUTATIONAL STUDY ON HLTH RELATED PHENOMENA: MOLEC MODEL OF BIOL PROCESSES

生物化学和化学分子模拟中心 流程. 分子建模已经成为一个重要的工具， 生物医学研究活动。 该研究旨在 对现象的计算研究，这将导致更好的 了解生物和生物化学的分子基础 流程. 化学系的几位教员 和生物学将参与支持的研究活动， 分子建模和计算化学预测。 之间 这些研究项目是研究DNA的光裂解， 拉曼光谱在多环芳烃中的应用 监测乳房组织损伤， 砷和阿特拉津在大鼠和鱼类中的作用， 影响透镜和角膜结构完整性的药剂，和 不同环境影响的计算研究 DNA自发突变的概率 最后一个项目是 纯粹的合作;所有其他研究计划将结合联合收割机 实验研究和计算密集型计算， 将需要复杂的分子建模和计算 基础设施演进 该中心的成立将促进 在JSU的合作研究工作，并将创建一个中心， 为来自杰克逊地区的教职员工提供计算生物医学研究 大学和医疗中心。

A Center for Molecular Modeling of Biochemical and Chemical Processes. Molecular modeling has become an essential tool in biomedical research activities. The proposed research is directed towards computational studies of phenomena which will lead to a better understanding of molecular bases of biological and biochemical processes. Several faculty members of the Departments of Chemistry and Biology will be involved in the research activities supported by the molecular modeling and computational chemistry predictions. Among the research projects are studies of photocleavage of DNA by Polycyclic Aromatic Hydrocarbons, application of Raman spectroscopy in monitoring breast tissue damage, investigations of acute toxicity of arsenic and atrazine in rats and fish, study of the effect of various agents on the structural integrity of the lens and cornea, and computational studies of different environmental effects on the probability of spontaneous mutations in DNA. The last project is purely co mputational; all other research initiatives will combine experimental studies and computationally intensive calculations which will require sophisticated molecular modeling and computational infrastructure. The establishment of the Center will facilitate collaborative research efforts at JSU and will create a hub for computational biomedical studies for faculty members from Jackson area colleges and medical centers.