Core--Clinical trials office

临床试验共享资源（CTSR）的主要任务是协助癌症中心的研究人员开发、激活和完成科学有效的临床试验，以一种有组织、成本效益和方法上合理的方式。为了提高临床试验支持人员的工作效率，所有从事癌症临床试验活动的机构数据管理人员、研究护士和文书人员被合并为一个共享资源，由Barbara Murphy博士和Debbie Wujcik女士，R.N， M.S.N指导。这一合并允许汇集支助资金，并允许最大限度地利用这些资金。CTSR旨在促进研究者发起的研究。CTSR的主要职责包括：1)协议支持服务，包括协议激活和监控；2)提供数据管理服务；3)提供研究护理支持。为了以有组织和统一的方式提供这些服务，服务被分为三类：核心服务、数据管理服务和研究护理服务。CTSR致力于在特定的调查领域促进科学合理的研究项目。这是通过特定疾病和特定模式的研究小组完成的，该小组由医师调查员、数据管理人员、护士和对特定恶性肿瘤或恶性肿瘤类别（如胸部肿瘤）感兴趣的相关工作人员组成。研究小组负责：1)方案审查和程序开发；2)通过IRB和科学评审委员会启动方案；3)符合条件的患者的识别、同意和登记；4)数据采集、数据管理和质量控制；5)向参与VCC的研究人员提供方案信息。在CTSR工作人员的协助下，医师团队领导定期召开会议，审查方案累积信息、数据管理活动、工作量和不良事件。此外，团队审查和评估新的协议，设置程序和研究优先级，并做出有关资源分配的决定。

The primary mission of the Clinical Trials Shared Resource (CTSR) is to assist Cancer Center investigators develop, activate and complete scientifically valid clinical trials in an organized, cost-effective and methodologically sound manner. To enhance the efficiency of clinical trials support staff, all institutional data managers, research nurses and clerical staff engaged in cancer clinical trials activity have been consolidated into a shared resource under the direction of Dr. Barbara Murphy and Ms. Debbie Wujcik, R.N., M.S.N.. This consolidation permits pooling of support dollars as well allowing for maximum utilization of such funding. The CTSR is designed to facilitate investigator- initiated research. The major areas of responsibility of the CTSR include: 1) protocol support services including protocol activation and monitoring, 2) provision of data management services and 3) provision of research nursing support. In order to provide these services in an organized and uniform manner, services have been grouped into three categories: Core Services, Data Management Services, and Research Nursing Services. The CTSR strives to facilitate scientifically sound research programs in specific areas of investigation. This is accomplished through disease-specific and modality-specific research teams which consist of physician investigators, data managers, nurses and associated staff with an interest in specific malignancy or category of malignancies (e.g. thoracic oncology). Research teams are responsible for: 1) protocol review and program development; 2) protocol activation through the IRB and scientific review committees; 3) identification, consent and registration of eligible patients; 4) data acquisition, data management and quality control; and 5) provision of protocol information to participating VCC investigators. With the assistance of CTSR staff, physician team leaders convene regular meetings during which there is review of protocol accrual information, data management activities and workload and adverse events. In addition, the teams review and evaluate new protocols, set program and study priorities, and make decisions regarding resource allocation.