NATURAL VITAMIN E IN CONTROLLING SYMPTOMS OF RHEUMATOID ARTHRITIS

欧洲的研究表明，在治疗关节炎的疼痛和僵硬方面，高剂量的维生素E可以和非甾体抗炎药（NSAIDs）如阿司匹林、萘普辛或伏他仑一样有效。然而，维生素E比非甾体抗炎药安全得多，因此它可能是治疗关节炎的更好选择。这是一项研究补充维生素E治疗RA患者的有效性和安全性。由于美国的大多数患者至少接受一种甚至多达四种药物的治疗，因此在没有其他药物的情况下研究维生素E治疗是不现实的。此外，维生素E不太可能被用作许多类风湿性关节炎患者的唯一药物治疗，即使它证明了它的益处。因此，最重要的临床试验应该设计为在典型的风湿性关节炎多模式治疗中，检查维生素E作为非甾体抗炎药的替代/辅助的潜在用途。

Studies in Europe have suggested that vitamin E in high doses can be as effective as nonsteroidal antiinflammatory drugs (NSAIDs) like aspirin, Naprosyn, or Voltaren in treating the pain and stiffness of arthritis. However, vitamin E is much safer than NSAIDs, so it could be a better alteranative for the treatment of arthritis. This is a study of the efficacy and safety of supplemental vitamin E therapy in patients with RA . Since most patients in the US are treated with at least one and as many as four medications, it is not realistic to study vitamin E therapy in the absence of other medications. Moreover, it is not likely that vitamin E would be used as sole drug treatment in many RA patients even with its demonstrated benefit. Thus the most important clinical trial should be designed to examine the potential use of vitamin E as an alternative/adjunct to NSAID in the typical multi-modality treatment of RA.