GCRC-CAP-WILLIAM HUNDLEY, M.D.

Bowman Gray/Baptist医院综合临床研究中心 1995年11月完成第一期项目。在此期间， 该中心取得了若干里程碑式的成就。 它作为一个 宝贵和广泛使用的机构资源， 几乎所有的临床和一些基础科学部门。大领域 调查包括心血管疾病，包括高血压和 脂质研究，重点研究妇女，非洲裔美国人和 老年人;营养与代谢;动脉粥样硬化;激素 女性替代疗法;癌症，包括前列腺癌、卵巢癌和 结直肠;新型脊髓麻醉药;心脏手术和 脑血管疾病;糖尿病和胰岛素敏感性;炎症， 包括营养和哮喘的研究;以及传染病， 包括败血性休克和艾滋病的研究。该中心还： 协助在《纽约时报》上发表完整期刊文章的研究 英国医学杂志和临床研究杂志。 成功竞争临床助理医师和计算机 数据库管理和分析系统资金。 设立了一个每周一次的系列研讨会，以培训年轻的调查人员， 30-45 M.D.博士学位。每周都有来自不同部门的人 本系列使用了多种格式的组合--来自高级编辑的提示和技巧 研究人员，技术专家的教学讲座，以及 由年轻的研究人员自己进行进展报告。 1994年赠款年度门诊量增加到6 400人次， 年度奖金100%。 1995年和1996年的预测是每年超过8 000人次。 在1994年的赠款年度，提供了7,500多份受控饮食，只有2份是全- 时间饮食人员。有了足够的人手，代谢厨房 在下一个项目中，数量可能会增加到每年17，000多餐 期 我们的GCRC只受到人力和财力资源的限制 由NIH提供。鲍曼·格雷的调查人员工作效率很高 并且对GCRC项目很有热情在下一个项目中 在此期间，将继续对当前的主要研究领域进行调查。 新的领域包括血栓形成、皮炎和造影剂肾病。的 GCRC的工作人员非常有能力，并致力于该计划的使命。 在这种环境下，我们的GCRC有能力远远超越 目前的水平。我们寻求五年的资金， 我们追求卓越的临床研究和研究培训。

The Bowman Gray/Baptist Hospital General Clinical Research Center will complete its first project period in November, 1995. During this time, the Center has achieved a number of milestones. It has served as a valuable and widely-used institutional resource, with investigators from nearly all clinical and some basic science departments. Major areas of investigation included cardiovascular disease, including hypertension and lipid research, with focused studies in women, African-Americans and the elderly; nutrition and metabolism, focusing in atherosclerosis; hormone replacement therapy in women; cancer, including prostate, ovarian and colorectal; new spinal anesthetic drugs; cardiac surgery and cerebrovascular disease; diabetes and insulin sensitivity; inflammation, including studies in nutrition and asthma; and infectious diseases, including studies in septic shock and AIDS. The GCRC also: assisted in research published as full journal articles in the New England Journal of Medicine and the Journal of Clinical Investigation. competed successfully for Clinical Associate Physician and Computerized Database Management and Analysis System funding. instituted a weekly seminar series to train young investigators, attended by 30-45 M.D.'s and Ph.D.'s from many different departments each week. This series uses a combination of formats - tips and tricks from senior investigators, didactic lectures by technical experts, and research-in- progress presentations by the young investigators themselves. grew outpatient visit volume to 6,400 for grant year 1994, exceeding the year's grant award by 100%. Projections for 1995 and 1996 exceed 8,000 visits per year. served over 7,500 controlled diets in grant year 1994 with only 2 full- time dietetic personnel. With sufficient staffing, the metabolic kitchen volume could grow to over 17,000 meals annually in the next project period. Our GCRC is constrained only by the human and financial resources provided to us by NIH. Bowman Gray investigators are highly productive and are very enthusiastic about the GCRC program. During the next project period, investigation will continue into current major research areas. New areas include thrombosis, dermatitis and contrast nephropathy. The GCRC staff is extremely capable and committed to the program's mission. Within this environment, our GCRC has the capacity to grow well beyond its current levels. We seek funding for a five-year period to continue our quest for excellence in clinical research and research training.