Vesicle dynamics (invited resubmission)

该方案将利用为天文学而开发的技术，但将把它们应用于活细胞生物学的测量。特别是，我们将应用开发的技术来测量大气引起的望远镜图像的失真，在生物学中的分泌过程的研究。这些过程的功能障碍知之甚少，但在发达国家造成约9%的死亡，仅糖尿病就造成英国约5%的死亡（英国心脏基金会统计数据）。该项目代表了生物学家，物理学家和数学家之间的合作，旨在高精度地监测分泌的动态。对这些动力学的研究将提高我们对癫痫、糖尿病、心脏病和哮喘等疾病的理解。这项研究还将使我们能够评估将天文学衍生技术应用于分子生物学研究的长期潜力。

The programme will exploit techniques developed for use in astronomy but will apply them to measurements in live-cell biology. In particular, we will apply a technique developed to measure atmopherically-induced distortion of telescope images to the study of secretion processes in biology. Malfunction of these processes is poorly understood but contributes to about 9% of fatalities in the developed world, diabetes alone contributes to ~5% of deaths in the UK (British Heart Foundation Statistics). This project represents a collaboration between biologists, physicists and mathematicians and aims to monitor the dynamics of secretion with high precision. The study of these dynamics will improve our understanding of diseases such as epilepsy, diabetes, heart disease and asthma. This study will also allow us to assess the longer-term potential for applying astronomy-derived techniques for molecular biology research.