CORE--CLINICAL TRIALS RESEARCH OFFICE

临床试验研究办公室（CTRO）提供基础设施和 促进必要的协调，以支持高质量的临床 在一个矩阵式癌症中心进行研究。科学的支持， CTRO涵盖了所有级别和类型的临床试验，从试点 研究和I期方案到II期和III期方案。这些 协议可以是UWCCC认证机构发起的机构或行业 申办的临床试验，也可能是NCI申办的临床试验 通过合作小组，第一阶段或研究补助金资助 机制等CTRO临床研究基础设施由 CCSG补助金旨在通过以下方式促进和促进临床研究 提供有效的质量控制和效率机制。 CTRO的UWCCC核心组件提供了基本级别的协议- 为所有UWCCC临床试验提供具体支持。这包括过程 协调;协议激活和关闭; UWCCC数据跟踪 基础;监管审查和合规性;患者登记和 随机化;和质量保证。CTRO支持该议定书 审查和监测系统，为质量控制提供检查点 以及执行机构权力以打开和关闭 协议.它确保完整报告方案活动， 癌症中心监督癌症临床研究 机构。

The Clinical Trials Research Office (CTRO) provides the infrastructure and facilitates the coordination necessary to support high quality clinical research in a matrix style cancer center. The science supported by the CTRO encompasses all levels and types of clinical trials, from pilot studies and phase I protocols through phase II and III protocols. These protocols may be UWCCC investigator-initiated institutional or industry sponsored clinical trials, or they may be NCI-sponsored clinical trials funded through the cooperative group, phase I, or research grant mechanisms. The CTRO infrastructure for clinical research supported by the CCSG grant is designed to facilitate and promote clinical research by providing effective mechanisms for quality control and efficiency. The UWCCC core component of the CTRO provides a basic level of protocol- specific support for all UWCCC clinical trials. This includes process coordination; protocol activation and closure; tracking by the UWCCC data base; regulatory review and compliance; patient registration and randomization; and quality assurance. The CTRO supports the Protocol Review and Monitoring System, providing checkpoints for quality control and for enforcement of the institutional authority to open and close protocols. It ensures complete reports on protocol activity and meaningful cancer center supervision of the cancer clinical research in the institution.