COOPERATIVE CORE LAB & CLINICAL NUTRITION RESEARCH UNIT
COOPERATIVE CORE LAB & CLINICAL NUTRITION RESEARCH UNIT
批准号:
6172304
负责人:
RICHARD S RIVLIN
金额:
$36.03万
依托单位国家:
美国
项目类别:
财政年份:
1985
资助国家:
美国
项目状态:
已结题
起止时间:
1985-07-01 至 2001-01-31
中文摘要
此修订后的竞争性续期申请的目的是
临床营养研究单位(CNRU)继续支持进一步
制定统一和连贯的营养方案,
癌症预防和控制的目的,
多学科研究,包括基础和临床,
为医科学生提供营养和癌症预防培训,
医生和其他卫生专业人员,改善临床护理,
癌症患者,特别是我们医疗中心的预防方面,
和一般人群,并提供准确的信息,
这是卫生专业人员和公众的共同责任。中央
我们的合作,机构间计划的重点仍然是营养,
癌症预防和控制。临床营养研究单位
是协调主要努力的中央机制,
这五个参与机构的重点:纪念斯隆-
凯特林癌症中心,纽约医院-康奈尔医学中心,
洛克菲勒大学,特殊外科医院和北
海岸大学医院。
CNRU的具体目标是开发七个组成部分,
总体方案,即:(l)对人类受试者和人口的研究,
(2)实验室调查,(3)共用设施和研究
服务,(4)研究培训,(5)医疗教育计划
学生、医院工作人员、执业医生和辅助医务人员,
(6)营养支助服务;(7)宣传活动。
实现这些目标的方法包括提供持续的支持
三个CNRU核心实验室-(a)免疫学,(B)脂质,和(c)
致癌作用和营养-并建立拟议的第四个核心小组
实验室(d)研究方法和分析。我们不寻求支持,
前代谢与肿瘤学核心实验室试点资金
研究使营养和癌症预防和控制的新想法成为可能
由新的和现有的调查人员进行测试。的丰富
计划提供了广泛的讲座,会议和会议,
促进科学家之间的互动,并使他们了解最新的
癌症预防和控制领域的进展。整体
CNRU的科学和行政进展由以下人员评估
外部和内部咨询委员会,与该计划进行协商
主任和行政核心。最新营养材料
由CNRU营养信息中心收集和传播
咨询委员会的建议。
迄今为止,CNRU所做的重点工作包括:
在方法和概念方面取得进展,
与癌症预防有关的营养学和临床研究,
控制,提高对营养在健康中的重要性的认识
专业人士和发展的第一个必要的营养教学,
康奈尔大学医学院的医学生。
英文摘要
The objective of this revised competitive renewal application for a
Clinical Nutrition Research Unit (CNRU) continues to be to support further
development of a unified and coherent program in nutrition in relation to
cancer prevention and control for the purposes of advancing
multidisciplinary research, both basic and clinical, upgrading the
training in nutrition and cancer prevention for medical students,
physicians and other health professionals, improving the clinical care of
cancer patients, particularly preventive aspects at our medical centers
and in the population in general, and providing accurate information on
this subject to health professionals and the general public. The central
focus of our collaborative, interinstitutional program remains nutrition,
cancer prevention and control. The Clinical Nutrition Research Unit
represents the central mechanism for coordinating the major efforts on
this focus of the five participating institutions: Memorial Sloan-
Kettering Cancer Center, The New York Hospital-Cornell Medical Center, The
Rockefeller University, The Hospital for Special Surgery and The North
Shore University Hospital.
The specific aims of the CNRU are to develop seven components in this
overall program, namely: (l) Research with human subjects and population,
(2) Laboratory investigations, (3) Shared facilities and research
services, (4) Research training, (5) Education programs for medical
students, house staff, practicing physicians and paramedical personnel,
(6) Nutritional support services, and (7) Public information activities.
The methods for achieving these goals include providing continuing support
for three CNRU Core Laboratories -- (a) Immunology, (b) Lipids, and (c)
Carcinogenesis and Nutrition -- and establishing a proposed fourth Core
Lab (d) Research Methodology and Analysis. We are not seeking support for
the former Metabolism & Oncology Core Lab at this time. Funds for pilot
studies enable novel ideas in nutrition and cancer prevention and control
to be tested by both new and established investigators. An enrichment
program provides a wide range of lectures, conferences and meetings to
stimulate interactions among scientists and to keep them current on
advancements in the field of cancer prevention and control. The overall
scientific and administrative progress of the CNRU is evaluated by
External and Internal Advisory Committees, who consult with the program
director and the Administrative Core. Up-to-date materials in nutrition
are collected and disseminated by the CNRU Nutrition Information Center
with advice from a Lay Advisory Committee.
Highlights made possible by the CNRU to date consist of significant
progress in making methodological and conceptual advances in both basic
and clinical research in nutrition in relation to cancer prevention and
control, increasing awareness of the importance of nutrition among health
professionals and developing the first required teaching of nutrition for
medical students at Cornell University Medical College.
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The effect of dietary protein on cystine excretion in patients with cystinuria.
膳食蛋白质对胱氨酸尿症患者胱氨酸排泄的影响。
DOI:
--
发表时间:
1984
期刊:
Clinical nephrology
影响因子:
1.1
作者:
[Rodman,JS, Blackburn,P, Williams,JJ, Brown,A, Pospischil,MA, Peterson,CM]
通讯作者:
Peterson,CM
Preventing hyperphagia normalizes 3-hydroxy-3-methylglutaryl-CoA reductase activity in small intestine and liver of diabetic rats.
预防食欲过盛可以使糖尿病大鼠小肠和肝脏中的 3-羟基-3-甲基戊二酰辅酶 A 还原酶活性正常化。
DOI:
--
发表时间:
1982
期刊:
Journal of lipid research
影响因子:
6.5
作者:
[Young,NL, Saudek,CD, Walters,L, Lapeyrolerie,J, Chang,V]
通讯作者:
Chang,V
Bone histomorphometry in men with spinal osteoporosis.
患有脊柱骨质疏松症的男性的骨组织形态测量。
DOI:
10.1007/bf00301602
发表时间:
1995
期刊:
Calcified tissue international
影响因子:
4.2
作者:
[Delichatsios,HK, Lane,JM, Rivlin,RS]
通讯作者:
Rivlin,RS
Negative growth regulation of oncogene-transformed human breast epithelial cells by phytochemicals. Role of apoptosis.
植物化学物质对癌基因转化的人乳腺上皮细胞的负生长调节。
DOI:
10.1111/j.1749-6632.1999.tb08742.x
发表时间:
1999
期刊:
Annals of the New York Academy of Sciences
影响因子:
5.2
作者:
[Katdare,M, Jinno,H, Osborne,MP, Telang,NT]
通讯作者:
Telang,NT
HER-2/neu amplification and overexpression in primary human breast cancer is associated with early metastasis.
原发性人类乳腺癌中 HER-2/neu 扩增和过度表达与早期转移相关。
DOI:
--
发表时间:
1992
期刊:
Anticancer research
影响因子:
2
作者:
[Tiwari,RK, Borgen,PI, Wong,GY, Cordon-Cardo,C, Osborne,MP]
通讯作者:
Osborne,MP
共 148 条
Collaborative Program in Nutrition and Cancer Prevention (PNCP)
-
批准号:7286651
-
项目类别:
-
资助金额:$51.09万
-
财政年份:2006
-
负责人:RICHARD S RIVLIN
-
依托单位:
Collaborative Program in Nutrition and Cancer Prevention (PNCP)
-
批准号:7094696
-
项目类别:
-
资助金额:$51.04万
-
财政年份:2006
-
负责人:RICHARD S RIVLIN
-
依托单位:
Human Subjects Research Enhancements Program
-
批准号:6591454
-
项目类别:
-
资助金额:$10.0万
-
财政年份:2002
-
负责人:RICHARD S RIVLIN
-
依托单位:
Human Subjects Research Enhancements Program
-
批准号:6778012
-
项目类别:
-
资助金额:$10.0万
-
财政年份:2002
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
-
批准号:3093280
-
项目类别:
-
资助金额:$46.82万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
-
批准号:3093285
-
项目类别:
-
资助金额:$51.38万
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财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
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批准号:3093286
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项目类别:
-
资助金额:$56.73万
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财政年份:1985
-
负责人:RICHARD S RIVLIN
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依托单位:
COOPERATIVE CORE LAB & CLINICAL NUTRITION RESEARCH UNIT
-
批准号:2087935
-
项目类别:
-
资助金额:$74.9万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
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依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
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批准号:2087932
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项目类别:
-
资助金额:$60.44万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB & CLINICAL NUTRITION RESEARCH UNIT
-
批准号:2894527
-
项目类别:
-
资助金额:$94.71万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
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批准号:3093289
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项目类别:
-
资助金额:$57.3万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
-
批准号:3093288
-
项目类别:
-
资助金额:$59.28万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
Cooperative Core Lab and Clinical Nutrition Research
-
批准号:6421034
-
项目类别:
-
资助金额:$66.4万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
Cooperative Core Lab and Clinical Nutrition Research
-
批准号:6750684
-
项目类别:
-
资助金额:$68.89万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
-
批准号:3093282
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项目类别:
-
资助金额:$40.0万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB & CLINICAL NUTRITION RESEARCH UNIT
-
批准号:2390639
-
项目类别:
-
资助金额:$76.81万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB & CLINICAL NUTRITION RESEARCH UNIT
-
批准号:2683419
-
项目类别:
-
资助金额:$79.17万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
COOPERATIVE CORE LAB AND CLINICAL NUTRITION RESEARCH
-
批准号:3093287
-
项目类别:
-
资助金额:$55.08万
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财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
Cooperative Core Lab and Clinical Nutrition Research
-
批准号:7050132
-
项目类别:
-
资助金额:$81.54万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
Cooperative Core Lab and Clinical Nutrition Research
-
批准号:6954825
-
项目类别:
-
资助金额:$42.25万
-
财政年份:1985
-
负责人:RICHARD S RIVLIN
-
依托单位:
海外基金