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ALOPECIA AREATA REGISTRY

ALOPECIA AREATA REGISTRY
斑秃登记处
批准号:
6358789
负责人:
MADELEINE DUVIC
金额:
$58.39万
依托单位国家:
美国
项目类别:
财政年份:
2000
资助国家:
美国
项目状态:
已结题
起止时间:
2000-09-28 至 2005-09-29

项目摘要

项目成果

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中文摘要
翻译
斑秃是一种相当常见的疾病,毛发从部分头皮、整个头皮或整个身体脱落。在某些情况下,这种疾病是遗传性的。它被认为是一种自身免疫性疾病。斑秃登记处将收集这三种类型的临床特征良好的患者:斑秃、斑秃(头皮毛发片状脱落)、全秃发(头皮毛发全部脱落)和全面性脱发(全身所有毛发完全脱落)。这将是一个患者的集合,既有多代家庭的患者,也有有对照的同胞对患者。这些特征良好的患者将被用于搜索人类基因组中与疾病相关的基因和/或基因,并将建立一种机制,允许有兴趣进行这种疾病的病理生理学或治疗研究的研究人员与具有所述研究的适当疾病形式的患者接触。
英文摘要
Alopecia Areata is a fairly common disease in which hair is lost either from part of the scalp, all of the scalp or the entire body. In some cases the disease is hereditary. It is thought to be an autoimmune disease. The Alopecia Areata Registry will collect clinically well characterized patients with these three forms of Alopecia Areata, alopecia areata (patchy loss of the scalp hair), alopecia totalis (total loss of all scalp hair) and alopecia universalis (complete loss of all hair everywhere on the body). This will be a collection of patients both in multi generational families and in sib pairs with controls. These well characterized patients will be used to search the human genome for disease associated loci and/or genes and a mechanism will be put in place to allow researchers interested in doing pathophysiology or treatment studies of this disease to be put in contact with patients having the appropriate form of the disease for the studies in question.
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