Electrochemical Enzyme Immunoassay to Test Blood HBV

描述(由申请者提供)：数百万美国人感染了 乙肝病毒(乙肝病毒)--其中许多人没有理由相信自己是 被感染了。有必要追踪美国数以百万计的乙肝病毒受害者--正如 以及相应的对创新技术的需求，以检测血液中的乙肝病毒。 显然，乙肝病毒是国家医学的优先事项。 该项目的总体目标是进一步开发并集成核心 传感器和酶免疫分析技术转化为一种新的快速 以及准确测量血液中的乙肝病毒水平。我们的目标是诊断 (检测)应用以及定量测量需求(用于监控 病毒水平和治疗效果)。我们方法的可行性是 在第一阶段清楚地展示了第二阶段的目标是 演示/验证/优化独特的电化学集成 专有电化学酶免疫测定法的测定方法 架构，以产生新的诊断/监控功能，以实现“实时、 在门诊环境中进行具有成本效益的乙肝病毒评估。 我们设想的产品是一种一次性的乙肝测试试纸，可以通过 便宜的、小的(手持)仪器。这将代表着一个关键的发展 在医疗诊断方面，将解决国内和国际上的主要问题 市场对低成本乙肝病毒筛查和监测的需求。 建议的商业应用：不可用

DESCRIPTION (provided by applicant):Millions of Americans are infected by the hepatitis B virus (HBV)-many of whom have no reason to believe they are infected. There is a need to track down America's millions of HBV victims-as well as a corresponding need for innovative technology to test blood for HBV. HBV is clearly a national medical priority. The overall goal of this project is to further develop and then integrate core sensor and enzyme immunoassay technologies into a novel technique for the rapid and accurate measurement of HBV levels in blood. We are targeting diagnostic (detection) applications as well as quantitative measurement needs (to monitor viral levels and treatment efficacy). The feasibility of our approach was clearly demonstrated during Phase I. The Phase II goal is to demonstrate/validate/optimize the integration of a unique electrochemical measurement method with proprietary electrochemical enzyme immunoassay architecture to produce a new diagnostic/monitoring capability for "real time," cost-effective HBV assessment in an outpatient setting. The product we envision is a disposable HBV test strip that can be read by an inexpensive, small (hand-held) instrument. It would represent a key development in medical diagnostics that would address major domestic and international market needs for low-cost HBV screening and monitoring. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE