NEUROSCIENCE TRAINING PROGRAM

这是一项新的申请，要求提供资金，以支持为期两年的神经科学博士前培训。该培训计划强调多学科取向，NINDS使命的指导是促进神经系统疾病的预防、诊断和治疗工作以及对此目的至关重要的基础科学。该计划利用了科学家与基础和临床科室的初级预约人员密切互动的悠久传统，以及他们在基础研究和临床研究之间相互作用的正式和示范指导学生的可用性。导师包括30名获得壁外资助的神经科学家，他们的研究兴趣包括离子通道的生物物理和药理学特性；正常、发育和病理状态下的突触蛋白质和信号分子；心血管和自主神经调节；内脏疼痛机制；神经肌肉疾病；细胞和系统水平的皮质和皮质下组织；自闭症、抑郁症和精神分裂症的神经生物学；痴呆的诊断和治疗；以及高级认知过程(知觉、记忆、语言、情感和决策)的神经心理学和解剖学。更多的教职员工参与神经科学项目的教学、委员会工作和其他活动，并可以作为学生的共同导师。神经科学培训计划强调学生在一系列子学科中积累经验，使他们能够在快速发展的多学科学术环境中有效地发挥作用。学生选择课程作业和实验室轮换相结合，按照五个分支(细胞科学、发育科学、分子科学、系统科学和行为神经科学)的结构进行组织。该结构还作为主题整合的系列研讨会和期刊俱乐部的基础。第二年结束时有两部分的综合笔试和口试，之后的几年主要用于论文研究。本申请的津贴是为了支持学生在致力于特定研究方向之前的第一和/或第二年。

This is a new application requesting funds to support two years of broad predoctoral training in Neurosciences. The training Program emphasizes a multidisciplinary orientation, as is guided by the NINDS mission to foster work toward the prevention, diagnosis, and treatment of nervous system disorders and the basic sciences fundamental to this purpose. The Program draws on a long tradition of close interactions between scientists with primary appointments in basic and clinical departments, and their availability to instruct students, both formally and by example, in the interplay between basic and clinical research. Mentors include 30 extramurally-funded neuroscientists with research interests focused on biophysical and pharmacological properties of ion channels; synaptic proteins and signaling molecules in normal, developmental, and pathological states; cardiovascular and autonomic regulation; visceral pain mechanisms; neuromuscular diseases; cortical and subcortical organization at a cellular and systems level; neurobiology of autism, depression, and schizophrenia; diagnosis and treatment of the dementias; and the neuropsychology and anatomy of higher cognitive processes (perception, memory, language, emotion, and decision making). A larger faculty pool participates in teaching, committee work, and other activities of the Neuroscience Program, and can serve as co-mentors for students. The Neuroscience Training Program emphasizes that students gain experience in a range of subdisciplines, to allow them to function effectively in a rapidly evolving multidisciplinary academic environment. Students take a combination of coursework and laboratory rotations, organized within the structure of five subdivisions (cellular, developmental, molecular, systems, and behavioral neuroscience). The structure also serves as the basis for a thematically integrated seminar series and journal clubs. There is a two-part written and oral Comprehensive exam at the end of the second year, with subsequent years devoted primarily to thesis research. Stipends from the present application are meant to support students in their first and/or second year, prior to their commitment to a specific research direction.