Core--Cohort Facility

招募和保留研究对象是研究中最困难的组成部分之一。在处理脆弱和难以接触的人群，如市中心的少数民族青少年时，这种困难更加严重。招募和保留研究对象既费时又费力，如果做得不好，可能会妨碍研究人员回答关键科学问题的能力。队列核心的总体目标是为招募、同意、筛选、登记和保留研究对象提供后勤支持，并收集旧金山青少年和性传播疾病CRC （SFCRC）所有项目所需的适当访谈和生物学数据。本核心的目标是提供一切必要的支持，以确保SFCRC的各个项目获得实现其特定目标所需的数据。由于个体将以有组织的方式进行识别和招募，因此可以进行多项研究，而不会在社区内造成混乱。集中征聘模式允许同时执行若干项研究以及将来扩大项目，而不损害为进行最初项目而建立的机会、认识和可接受性。具体来说，这个队列核心的目标是：1。从通过随机数字拨号确定的目标人群中招募、同意、筛选和招募随机家庭概率的青少年指数受试者（项目1、2、3）2。招募、同意并招募两代青少年指标受试者的性伴侣（项目1、3）。招募、同意、筛选和招募性经验不足的女性青少年指标受试者的女性社会伴侣（项目2,3）。跟踪并保留研究对象以供后续研究（项目1、2、3）确保成功收集研究对象的访谈数据和生物标本（项目1、2、3）

Recruitment and retention of study subjects is one of the most difficult components of research. This difficulty is compounded when dealing with vulnerable and hard-to-reach populations such as inner-city, minority adolescents. Recruitment and retention of study subjects can be both labor- and time-intensive and if not done properly can impede researchers' ability to answer critical scientific questions. The overall objective of the Cohort Core is to provide the logistical support to recruit, consent, screen, enroll and retain study subjects and to collect the appropriate interview and biological data as needed for all projects of the San Francisco Adolescents and STDs CRC (SFCRC). It is the goal of this Core to provide all necessary support to ensure that the individual projects of the SFCRC receive the data needed to achieve their specific aims. Because individuals will be identified and recruited in an organized manner, multiple studies can be ongoing without creating confusion within the community. A centralized recruitment model allows for the implementation of several studies simultaneously as well as for future expansion of projects without jeopardizing the access, aware and acceptability established to conduct the initial projects. Specifically, the aims of this Cohort Core are to: 1. Recruit, consent, screen, and enroll a random household probability sample of adolescent index subjects from the target population identified through random-digit dialing 9Projects 1, 2, 3) 2. Recruit, consent, and enroll two generations of adolescent index subjects' sex partners (Projects 1, 3) 3. Recruit, consent, screen, and enroll female social partners of sexually inexperienced female adolescent index subjects (Projects 2, 3). 4. Track and retain study subjects for follow-up (Projects 1, 2, 3) 5. Ensure successful collection of interview data and biological specimens from study subjects (Projects 1, 2, 3)