PERFUSION IMAGING OF BRAIN, KIDNEY, & HEART

该中心已规定使用其资源进行试点 和可行性实验进行，而不需要 请科学咨询委员会审查。 这些 实验通常持续时间很短， 目的是获得非常有限的数据集。 这些资源 由署长酌情分配。 NMR中心拥有 在这方面协助了几个小组：（一）获得高分辨率MR 大鼠大脑的图像，用于制备 用于PET数据大鼠大脑，（ii）获得高分辨率MR图像 一个孤立的人心脏标本的生物力学建模的 心脏，（iii）获得固定人脑的高分辨率MR图像， (iv)获得大鼠模型脑灌注图的额外数据 蛛网膜下腔出血的病人来完成一项研究， （v）获得表观扩散系数（ADC） 光血栓溶解性卒中大鼠脑的图和灌注图 模型 分配有限的核磁共振中心的时间， 扫描仪及时提供了一个非常有用的目的， 调查人员的数据，有时需要最少的 延迟 在过去，一些调查人员曾利用这一点， 署长为申请而取得试验数据的酌情决定时间 资助，进行可行性研究， 用于设计新的实验， 在核磁共振中心作为定期项目，并捆绑松散的结束， 以前在中心做过实验。

The Center has provision for the use of its resources for pilot and feasibility experiments to be carried out without the need for the request to be reviewed by the Scientific Advisory Committee. These experiments are usually of short duration and carried out for the purpose of obtaining a very limited set of data. These resources are allocated at the discretion of the Director. The NMR Center has assisted several groups in this regard: (i) obtain high resolution MR images of the rat brain for the purpose of preparing an atlas of the rat brain for use with PET data, (ii) obtain high-resolution MR images of an isolated human heart specimen for modeling biomechanics of the heart, (iii) obtain high-resolution MR images of a fixed human brain, (iv) obtain additional data on cerebral perfusion maps of a rat model with subarachnoid hemorrhage to complete a study that was carried out the previous year, and (v) obtain apparent diffusion coefficient (ADC) maps and perfusion maps of the rat brain in a photothrobolytic stroke model. Allocation of a limited amount of NMR Center's time on the scanners in a timely manner serves a very useful purpose of providing the investigators data which are sometimes required with minimal delay. In the past, a number of investigators have used this Director's discretionary time for obtaining pilot data for applying for grant support, for carrying out feasibility studies which were used in designing new experiments that were subsequently carried out in the NMR Center as regular projects, and for tying up loose ends of previosly carried out experiments in the Center.