PSYCHOSOCIAL INTERVENTION FOR ORAL CANCER PATIENTS

口腔癌对健康和福祉构成重大威胁。它是由多种环境、遗传、病毒和行为因素引起的，包括吸烟和饮酒。由于手术可能会毁容，治疗对身体形象构成威胁。死亡和/或疾病复发的威胁、沟通问题以及进食和呼吸困难也是可能的。此外，治疗需要停止使用烟草和酒精。这些都是可能影响心理调整和生活质量的重要压力源。然而，综合社会心理干预已应用于口腔癌。尽管可能与口腔癌相关的重大痛苦以及最近团体和个人干预在增强适应和减轻压力方面的成功，但没有系统的数据与口腔癌患者的这些问题有关。拟议的研究将完成对口腔癌患者的社会心理干预的开发，并将评估这种干预在减轻压力、促进戒酒和戒烟、减少心理困扰和提高生活质量方面的有效性。本研究将是一项针对口腔癌患者的心理社会干预的随机调查，涉及口腔癌患者干预组和对照组的一系列结果的比较。随机分配到实验组的患者将在术后住院期间开始接受七期心理社会干预。控制组的患者将在7个简短的会议中接受有关口腔癌及其治疗的信息，这些信息将由负责干预的同一位治疗师提供。所有参与者将完成干预前评估，并在干预后1个月和6个月以及一年后提供类似的数据。干预的评估将通过比较接受干预的患者和接受信息和标准护理的类似患者的对照组的几种心理和医疗结果来完成。结果将包括压力、焦虑、抑郁、吸烟、戒烟和生活质量的测量。还将监测与疾病有关的结果（例如疾病的新证据）。

Oral cancer constitutes a significant threat to health and well being. It is caused by a variety of environmental, genetic, viral, and behavioral factors including tobacco and alcohol use. Treatment poses threats to body image due to potentially disfiguring surgery. Threats of death and/or recurrence of disease, communication problems, and eating and breathing difficulties are also possible. In addition, treatment requires cessation of tobacco and alcohol use. These are significant stressors that are likely to affect psychological adjustment and quality of life. However, comprehensive psychosocial interventions have been applied to oral cancers. Despite the likelihood of significant distress associated with oral cancer and the recent success of group and individual interventions in enhancing adjustment and reducing stress, there are no systematic data bearing on these issues in oral cancer patients. The proposed research will complete development of a psychosocial intervention for oral cancer patients and will evaluate the effectiveness of this intervention in reducing stress, facilitating alcohol and tobacco cessation, reducing psychological distress, and enhancing quality of life. This study will be a randomized investigation for the psychosocial intervention for oral cancer patients involving comparison of a range of outcomes among intervention and control groups of oral cancer patients. Patients randomized to the experimental group will receive a seven-session psychosocial psychosocial intervention, beginning during post-surgery inpatient hospitalization. Patients in the control group will receive information about cancer of the oral cavity and its treatment in seven brief session with the same therapist who administers the intervention. All participants will complete a pre-intervention assessment and will provide similar data one and six months after the intervention and one year later. Evaluation of the intervention will be accomplished by comparing several psychological and medical outcomes of patients receiving the intervention and the control group of similar patients who receive information and standard care. Outcomes will include the measures of stress, anxiety, depress, smoking, smoking cessation, and quality of life. Disease related outcomes (e.g new evidence of disease) will also be monitored.