A novel non-invasive diagnostic imaging technique of metastatic cancer using plasminogen activator inhibitor type 2.

该项目旨在开发一种基于无毒蛋白(PAI2)的非侵入性肿瘤诊断显像剂，我们知道PAI2专门识别恶性肿瘤的关键标志。PAI2将用常用的成像放射性同位素进行标记。这种新的成像技术具有重要的潜在临床应用，包括为个别患者确定最合适的治疗方法，评估这些治疗的成功，以及一种新的非侵入性恶性肿瘤预后指标。

This project aims to develop a non-invasive tumour diagnostic imaging agent based on a non-toxic protein (PAI2) that we know specifically identifies a critical marker of malignancy. PAI2 will be labelled with commonly used imaging radioisotopes. This novel imaging technique has important potential clinical uses including, determination of the most appropriate treatment for individual patients, assessing the success of such treatments, and a novel non-invasive prognostic indicator of malignancy.