High spatial resolution dosimetry for radioactive plaques used for radiotherapy of eye lesions

用于眼部病变放射治疗的放射性斑块的高空间分辨率剂量测定

• 批准号: nhmrc : 573428
• 负责人: A/Pr Martin Carolan
• 金额: $ 23.82万
• 依托单位: University of Wollongong
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/high-spatial-resolution-eye-lesions/77839
• 关键词: spatial; resolution; dosimetry; radioactive; plaques

Melanoma and squamous cell carcinoma are the commonest ocular malignancies in adults. While plaque brachytherapy has delivered advances in ocular cancer management, significant challenges remain. These include post-treatment vision loss (due to over irradiation of vital structures, e.g. optic nerve), treatment failure (~10%) and an inability to treat large tumours (>8mm thick). This project aims to address these challenges through rigorous quality assurance and enhanced dosimetry planning.

黑色素瘤和鳞状细胞癌是成人最常见的眼部恶性肿瘤。虽然斑块近距离治疗在眼癌治疗方面取得了进展，但仍存在重大挑战。这些包括治疗后视力丧失（由于重要结构，如视神经的过度照射）、治疗失败（约10%）和无法治疗大肿瘤（8mm厚）。该项目旨在通过严格的质量保证和加强剂量学规划来应对这些挑战。