TRAINING FUTURE GENERATIONS OF MENTAL HEALTH RESEARCHERS

这个R25应用程序围绕两个总体主题组织--在基础研究和临床研究之间搭建桥梁，在科学和临床服务之间搭建桥梁。我们计划进一步发展在翻译和公共卫生模式框架内进行临床研究培训所需的基础设施。我们计划的一个关键前提是在神经科学、神经成像和遗传学之间建立联系，并将它们应用于终生精神和身体疾病的干预。我们还计划在我们建立的在对照临床试验中进行的治疗结果研究的传统与NIMH目前给予干预研究更多公共健康导向的优先事项之间建立桥梁。我们的具体目标包括：(1)制定一项初级教师学者计划，为由我们的研究、教育和培训中心(RETC)执行委员会竞争性挑选的教师提供两年25%的工资支持。短期目标是促进这些教师开发K奖职业发展应用程序；长期目标是确保他们作为从事临床研究的独立研究人员取得成功；(2)开发有两个轨道的课程-一个用于翻译研究，另一个用于干预研究。这两个项目将包括：(1)在学年举办1个小型课程(10节)和2个密集暑期工作坊(各1周)；(3)为初级学院学者收集初步数据以支持其K奖申请提供4个奖项；以及(4)聘请1名全职统计员，为初级学院学者提供支持。讨论了与招聘代表性不足的少数族裔和妇女有关的问题，并描述了评估该方案成功的具体标准(例如，增加资助的早期职业发展奖和职业生涯中期以病人为导向的研究奖)。

This R25 application is organized around two overall themes-building bridges between basic and clinical research and building bridges between science and clinical service. We plan to develop further the infrastructure needed to conduct clinical research training within the frameworks of both translational and public health models. A key premise of our program is the importance of forging links between neuroscience, neuroimaging, and genetics and their applications to interventions with psychiatric and physical illnesses throughout the lifespan. We also plan to build bridges between the tradition we have established of treatment outcome research done in controlled clinical trials and the current priority accorded by NIMH to intervention research with an increased public health orientation. Our specific aims include: (1) development of a Junior Faculty Scholars Program that will provide 25 percent salary support for two years to faculty members selected competitively by the Executive Committee of our Research Education and Training Center (RETC). The short-term goal is to facilitate the development of K-award career development applications by these faculty; the long-term goal is to ensure their success as independent investigators doing clinical research; (2) development of a curriculum with two tracks-one for translational research and a second for intervention research. Both tracks will involve one mini-course during the academic year (10 sessions) and two intensive summer workshops (one week each); (3) provision of four awards for pilot research studies by Junior Faculty Scholars collecting initial data in support of their K-award applications; and (4) hiring of one full-time statistician who will provide support to the Junior Faculty Scholars. Issues regarding recruitment of underrepresented minorities and women are addressed, and specific criteria for evaluating the success of the program (e.g., an increase in funded early career development awards and mid-career patient-oriented research awards) are also described.