CLINICAL NEUROSCIENCE MENTAL HEALTH RESEARCH TRAINING

神经科学研究的进步使得发现许多精神疾病的生物学原因和发病机制成为现实，这反过来将为开发改进的治疗方法、预防疾病和治愈患者提供主要途径。我们的目标是建立一个培训计划，以吸引和吸引医学学生、研究生、博士后研究员和精神科住院医生从事转化临床神经科学研究，在那里他们将把基础神经科学的知识应用到精神病学的临床研究中。该计划将包括两个部分：1)现代精神病学导向的教学课程，将基础和临床神经科学与临床精神病学相结合；2)12个月的全日制结构化和指导的临床神经科学研究培训经验。课程的特点是跨学科的整合，重点是理解精神疾病。病例报告、现场访谈和视频剪辑将用于说明基础神经科学各个方面的临床相关性。每年课程的核心方面将以互动讲座的形式呈现给200名一年级和二年级的医学生，30名研究生，17名精神科住院医生和35名博士后。该计划的一个新颖和独特的方面是开发和使用广泛的交互式电子教学大纲，涵盖课程的各个方面（即全文，计算机访问参考文献摘要和附加阅读，交互式图形，动画，录像带患者演示，以及自学和自我评估的机会）。所有参加讲座的学生、住院医师和研究员都可以在耶鲁大学的内联网上获得这些信息。该计划的一个关键方面是，被选中的个人有机会选择一个为期12个月的结构化和指导的临床研究培训经历，在那里他们将在自己进行临床神经科学研究的高级研究员的监督下接受特定临床研究方法的培训。教学课程和指导临床研究经验将专门针对参与者的教育水平和经验。整个项目将内置评估方法，并每年进行跟进。该方案的各个方面将作为可能在国家一级加以利用的样板。

Advances from neuroscience research now make it realistically possible to discover the biologic causes and pathogenesis of many psychiatric illnesses, and this in turn will provide the major avenues for developing improved treatments, prevention of illness, and cure of patients. Our goal is to construct a training program that will attract and engage medical students, graduate students, postdoctoral fellows, and psychiatric residents in translational clinical neuroscience research careers where they will apply knowledge from basic neuroscience to clinical research in psychiatry. The program will consist of two componets: 1) a modern psychiatry oriented didactic curriculum which integrates basic and clinical neuroscience with clinical psychiatry and, 2) full-time 12 month structured and mentored clinical neuroscience research training experiences. The curriculum is distinguished by its integration across disciplines with a focus on understanding psychiatric illness. Case reports, live interviews, and video clips will be used to illustrate the clinical relevance of each aspect of basic neuroscience. Each year core aspects of the curriculum will be presented in an interactive lecture format to 200 1st and 2nd year medical students, 30 graduate students, 17 psychiatric residents and 35 postdoctoral fellows. A novel and unique aspect of the program is the development and use of an extensive interactive electronic syllabus covering all facets of the curriculum (i.e. full text with computer access to abstracts of references and additional readings, interactive graphics, animation, video taped patient presentations, and opportunities for self study and self evaluation). This will be available on a Yale University Intranet to all students, residents, and fellows who attend the lectures. A key aspect of the program is the opportunity for selected individuals to elect a 12 month structured and mentored clinical research training experience where they will receive training in specific clinical research methods under the supervision of senior investigators who are themselves conducting clinical neuroscience research. The didactic curriculum and the mentored clinical research experiences will be specifically tailored to the educational level and experience of the participants. The entire program will have built in methods for evaluation with yearly follow up. Aspects of this Program will be available as a model for possible utilization at the national level.