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A prospective multicentre randomized study to evaluate the impact of OSA treatment with CPAP on atrial electrical and structural substrate and on long term maintenance of sinus rhythm following catheter ablation of atrial fibrillation

A prospective multicentre randomized study to evaluate the impact of OSA treatment with CPAP on atrial electrical and structural substrate and on long term maintenance of sinus rhythm following catheter ablation of atrial fibrillation
一项前瞻性多中心随机研究,旨在评估 OSA 联合 CPAP 治疗对心房电和结构基质以及房颤导管消融后长期维持窦性心律的影响
批准号:
nhmrc : 1151341
负责人:
金额:
$8.55万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Postgraduate Scholarships
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31

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中文摘要
翻译
心房颤动(房颤)是最常见的心律失常,可导致中风、心力衰竭和增加死亡率。同样,阻塞性睡眠呼吸暂停(OSA)也越来越被认为是一种现代流行病。流行病学数据表明,这两种疾病之间存在独立的关联。我们将进行一项前瞻性的多中心随机研究,以评估OSA治疗对以下方面的影响:(I)导管消融房颤后维持窦性心律,(Ii)心房结构和功能
英文摘要
Atrial fibrillation(AF) is the commonest heart rhythm disorder causing stroke, heart failure and increased mortality. Similarly, obstructive sleep apnea(OSA) is increasingly recognised as a modern epidemic. Epidemiological data have demonstrated an independent association between the two conditions. We will conduct a prospective multicenter randomized study to evaluate the impact of OSA treatment on: (i)maintenance of sinus rhythm after catheter ablation of AF, (ii)atrial structure and function
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