RES FACIL CONST: RHESUS MODEL, STEM CELLS

描述(由申请人提供)：本申请申请资金，以建设动物服务大楼(ASB)扩建二期填充物，将提供住房544非人类灵长类(HAP)在11,970平方米。英国《金融时报》最先进的设施。扩建将使俄勒冈州地区灵长类研究中心(ORPRC)能够满足快速增长的研究需求，并符合美国农业部(USDA)关于扩大社会住房的新规定标准。俄勒冈健康与科学大学(OHSU)做出了重大承诺，提供了大约400万美元的资金来建造一个35600平方米的建筑。英国《金融时报》壳牌加入ASB。第一阶段的填充物包括13,000平方英尺。英国《金融时报》可容纳最多192个NHP的设施，以及提供行为测试室、办公室和新的笼子洗涤区。各个研究领域的快速增长需要更多的NHP住房。目前的NHP住房已经满员，导致以下问题：1)满足现有研究计划或开始新项目的能力有限；2)延迟采购所需的动物；3)由于缺乏灵活的空间而推迟翻新；以及4)社会住房的延迟实施。本申请的具体目标是建造ASB扩建的第二阶段填充，包括动物生物安全2级(ABL2)安全壳，可容纳17个动物拘留室、一个饲料储存室和一个程序室，最多可容纳544个NHP。每个动物保育室将在成对的笼子中容纳32个HAP，以及大型集体游戏围栏，以允许动物群体定期体验增强的社会环境。

DESCRIPTION (provided by applicant): This application requests funds to construct Phase II infill to the Animal Services Building (ASB) addition that will provide housing for 544 non-human primates (NHPs) in an 11,970 sq. ft. state-of-the art facility. The expansion will enable the Oregon Regional Primate Research Center (ORPRC) to meet rapidly growing research needs, as well as comply with new United States Department of Agriculture (USDA) mandated standards for expanded social housing. The Oregon Health and Science University (OHSU) made a major commitment by providing approximately $4 million in funds to construct a 35,600 sq. ft. shell addition to the ASB. Phase I infill consists of a 13,000 sq. ft. facility that will house up to 192 NHPs, as well as provide behavioral testing rooms, and office and new cage wash areas. Rapid growth in various research areas necessitates additional NHP housing. Current NHP housing is full, resulting in the following problems: 1) limited ability to meet the needs of existing research programs or begin new projects; 2) delayed procurement of needed animals; 3) delayed renovations due to lack of flex space; and 4) delayed implementation of social housing. The Specific Aims of this application are to construct Phase II infill of the ASB addition, consisting of Animal Biosafety Level 2 (ABL2) containment housing for up to 544 NHPs in 17 animal holding rooms, a feed storage room and a procedure room. Each animal holding room will contain 32 NHPs in paired cages, as well as large group play enclosures to permit groups of animals to regularly experience an enhanced social environment.