Clinical Research Training For Studies of CVD in India

描述（由申请人提供）：冠心病的最高发病率 世界上的冠心病和糖尿病主要分布在印度和南亚。 这些疾病目前代表了与疾病相关的最重要的问题。 在这个种族群体中。亚拉巴马大学的研究人员在 伯明翰（UAB）和马德拉斯糖尿病研究基金会（MDRF） 已经开始合作解决这个重要的研究领域。MDRF 在开展大型流行病学研究方面表现出了非凡的能力 资源有限，调查人员接触有限， 流行病学培训。然而，尽管他们取得了成就， 是否需要进一步培训以增加基础？的能力进行 纵向流行病学研究和临床试验。目前的提案， 为了响应RFA TW-01-003，将迅速加速和加强现有的 两个机构之间的合作，提供培训方案， 为MDRF受训人员进行临床研究。为了完成培训，我们 将利用UAB的三大资源。第一是临床研究 培训计划（CRTP），申请的母基金， 制定了短期和长期培训内容， 目前的训练计划已经结束。第二个资源是专业知识， 心血管流行病学的联合教师的司 预防医学和公共卫生学院，包括几个 全国公认的教育工作者在该地区。最后，约翰·J·斯帕克曼 国际健康教育中心将提供行政和 协调培训所需的国际培训专门知识 活动UAB和马德拉斯的印度合作者将发挥主要领导作用 在培训和项目规划中的作用。四名学员将来到UAB， 长期培训，导致临床研究中的MSPH（为 每一项培训都是根据千年发展目标基金的研究成果在一个特定领域进行的 目的（流行病学，临床试验，生物统计学和遗传学）。两 一批学员将来到UAB进行为期60小时的短期培训， CRTP版本和其他相关教育经验;后续行动 一年后在MDRF举办的课程。区域培训将 通过UAB和MDRF教师在印度举办的讲习班提供， 南亚动脉粥样硬化和血栓学会（South Asian Society for Atherosclerosis and Thrombosis） 计划中的项目将提供一个已经很出色的印度研究中心 有大量训练有素的临床研究人员终极意义 该项目的一个重要意义是，它可能会导致治疗和预防策略， 是世界上最大的冠心病风险人群，还是世界的五分之一？S 人口

DESCRIPTION (provided by applicant): The highest rates of Coronary Heart Disease (CHD) and diabetes in the world are found in India and south Asia. These diseases presently represent the most important problems associated with aging in this ethnic group. Researchers at the University of Alabama at Birmingham (UAB) and the Madras Diabetes Research Foundation (MDRF) have already begun collaborating to address this vital area of research. The MDRF has shown remarkable abilities in carrying out large epidemiological studies with limited resources and investigators with limited exposure to epidemiological training. However, despite their accomplishments, there is a need for further training to increase the foundation?s abilities to conduct longitudinal epidemiological studies and clinical trials. The present proposal, in response to RFA TW-01-003, will rapidly accelerate and enhance the existing collaboration between the two institutions by providing a training program in clinical research for MDRF trainees. In order to accomplish the training, we will utilize three major UAB resources. The first is the Clinical Research Training Program (CRTP), the parent grant of the application, that has developed the short-term and long-term training components upon which the present training plan rests. The second resource is the expertise in cardiovascular epidemiology from the combined faculty of the Division of Preventive Medicine and the School of Public Health, including several nationally recognized educators in the area. Finally, the John J. Sparkman Center for International Health Education will provide the administrative and prior international training expertise needed to coordinate training activities. Indian collaborators at UAB and Madras will have major leadership roles in training and program planning. Four trainees will come to UAB for long-term training leading to a MSPH in Clinical Research (as developed for the parent grant), with each training in a specific area based on MDRF research objectives (epidemiology, clinical trials, biostatistics, and genetics). Two groups of trainees will come to UAB for short-term training involving a 60 hour version of the CRTP and other relevant educational experiences; a follow-up course to be given at the MDRF one year later. Regional training will be provided through workshops taught in India by UAB and MDRF faculty in association with the South Asian Society for Atherosclerosis and Thrombosis. The planned program will provide an already outstanding Indian research center with a critical mass of trained clinical researchers. The ultimate significance of this project is that it may lead to treatment and prevention strategies for the largest group at risk for CHD in the world, or one-fifth of the world?s population.