RISK REDUCTION IN HIV+/HIV-ALCOHOL ABUSING YOUTH

说明(摘自摘要)：在这项拟议的5年研究中， 研究人员将比较增强认知-行为的效果 (E-CB)对标准护理信息(SC-INFO)情况的干预 降低艾滋病毒传播风险(例如，受保护的比例 性行为、性伴侣数量、使用酒精或其他药物[新增] 性活动的近在咫尺)在一个文化多元化的内城，增加- 440名HIV阴性的青少年罪犯和50名HIV- 积极的青少年罪犯。他们的具体目标是评估：(1)如果 E-CB比SC-INFO更大程度地减少艾滋病毒危险行为；(2)如果 E-CB比SC-INFO更大程度地减少了AOD的使用；(3)如果AOD滥用 可能会调节我们的干预措施和艾滋病毒风险之间的关系 行为结果，(4)关键变量是否在 这些干预措施和艾滋病毒危险行为以及AOD滥用干预措施和 HIV危险行为和AOD滥用后果。探索性的目的是 评估HIV血清状态对结果变量的影响。这项研究是 意义重大，因为它解决了开发有效的 在不断增长的中国人口中减少艾滋病毒风险和AOD使用的干预措施 少年犯法庭下令接受治疗。这些人的需求 传统的AOD滥用并没有充分解决犯罪者的问题 由极高的复发率表明的治疗方案 不安全的性行为和酗酒/吸毒。此项目的特定功能 增加它将产生最终和创新的可能性 信息包括：(A)使用标准化的心理社会电子公民 专门为目标量身定做的干预措施 (B)采用随机化实验设计， 将分配到E-CB的受试者与分配到标准护理的受试者进行比较 情况；(C)干预发生的时间 从住院到门诊的有压力的过渡；和(D) 将艾滋病毒阳性青年纳入研究和验证 试图减少危险性行为和AOD使用行为的干预措施 混合血清状态组。

DESCRIPTION (adapted from the Abstract): In this proposed 5-year study the researchers will compare the effects of an Enhanced Cognitive-Behavioral (E-CB) Intervention to a Standard Care Information (SC-INFO) Condition in reducing the risk of HIV transmission (e.g., proportion of protected sexual acts, number of sex partners, use of alcohol or other drugs [ADD] proximal to sex activity) among a culturally diverse, inner city, ADD- abusing population of 440 HIV-negative adolescent offenders and 50 HIV- positive adolescent offenders. Their specific aims are to evaluate: (1) if E-CB reduces HIV risk behaviors to a greater extent than SC-INFO; (2) if E-CB reduces AOD use to a greater extent than SC-INFO; (3) if AOD abuse may mediate the relationship between our interventions and HIV risk behaviors outcomes, (4) if key variables mediate the relationships between these interventions and HIV risk behaviors and AOD-abuse interventions and the HIV-risk behavior and AOD-abuse outcome. The exploratory aim is to evaluate effects of HIV serostatus on outcome variables. The study is significant because it addresses the urgent need to develop an effective intervention to reduce HIV risk and AOD use in a growing population of adolescent offenders court ordered into treatment. The needs of these offenders have not been addressed adequately by traditional AOD-abuse treatment programs as indicated by an extremely high rate of relapse to unsafe sex and alcohol/drug abuse. Specific features of this project that increase the probability that it will produce definitive and innovative information include: (a) the use of a standardized, psychosocial E-CB intervention which has been specifically tailored for the target population; (b) the employment of a randomized experimental design that compares subjects assigned to E-CB with those assigned to a standard care condition; (c) the timing of the intervention to occur prior to the stressful transition from inpatient to outpatient status; and (d) the inclusion of HIV-positive youths in the study and validation of an intervention that attempts to reduce risky sex and AOD-using behaviors in mixed serostatus groups.