CLINICAL RESEARCH TRAINING PROGRAM

阿拉巴马大学（UAB）实施了一项全面的计划，以确保其临床研究活动的综合发展和持续卓越。对RFA OD-98-007的回应中描述的临床研究培训计划（CRTP）解决了迫切需要一个正式的计划，为实习临床研究者提供进行临床研究所需的技能和概念框架。在UAB和相关校园，大约有270人被确定为合格的潜在参与者。UAB-CRTP的目标是：1)识别和招募有动力成为独立临床研究人员的学员，并从必要的基本技能教学培训中受益；2)为未来临床研究者提供培训课程，使参与者能够发起和开展高质量的临床研究，向参与者灌输保护患者权利的伦理价值观，并进一步推动参与者的临床研究活动；3)认真评估项目，跟踪参与者的进度。这些目标将通过由UAB医学院与公共卫生学院密切合作管理的为期两年的项目来实现，并依靠来自几个不同学院研究项目的国家认可的教师的丰富多样性。由多学科课程委员会制定的课程将为20-25人的班级提供教学培训。在第一年，核心领域的80小时教学培训将以模块为基础的课程形式呈现。在第二年，将通过选修模块完成参与者特定兴趣领域的正式培训，并通过基于经验的学习计划进一步发展设计和分析技能。培训机会的广度和深度保证了学员的职业发展。课程的持续发展和监督将由内部咨询委员会监督的正式评价方案提供。UAB拥有完善的、资金充足的研究项目，并将为CRTP学员提供大量有动力的学员和大量高质量的研究机会。这项申请将利用UAB的创新研究（约2.6亿美元）和临床研究人员在服务少数民族人群方面的专业知识，特别是非洲裔美国人、农村、老年和儿科人群。

A comprehensive plan has been implemented at the University of Alabama (UAB) to ensure the integrated development and continued excellence of its clinical research activities. The Clinical Research Training Program (CRTP) described in this response to RFA OD-98-007 addresses the urgent need for a formal program to provide trainee clinical investigators with the skills and conceptual framework necessary for the conduct of clinical research Approximately 270 individuals have been identified as qualified, potential participants at UAB and associated campuses. The objectives of the UAB-CRTP are: 1) To identify and recruit trainees who are motivated to become independent clinical researchers and who would benefit from didactic training in the necessary fundamental skills; 2) To provide a curriculum for training of future clinical investigators that will enable participants to initiate and conduct high quality clinical research, instill in the participants the ethical values that protect patients' rights and further participants' clinical research activities; and 3) To carefully evaluate the program and track the progress of the participants. These objectives will be achieved through a 2-year program administered through the UAB School of Medicine in close cooperation with the School of Public Health and relying on the rich diversity of nationally recognized faculty drawn from the research programs of several different Schools. Didactic training will be provided to classes of 20-25 participants in a program developed by the multidisciplinary Curriculum Committee. In the first year, 80 hours of didactic training in core areas will be presented in a module-based program. In the second year, formal training in the participant's specific area of interest will be accomplished through elective modules, and an experienced-based learning program will be used for further development of design and analytical skills. The career development of the trainees is ensured by the breadth and depth of mentored training opportunities. Continuing development of the curriculum and oversight will be provided by a formal evaluation program with the oversight of the Internal Advisory Committee. UAB has well- established, well-funded research programs and will provide both a pool of motivated trainees and ample high quality research opportunities for the CRTP trainees. This application will leverage the innovative research at UAB (approximately 260 million dollars) and the expertise of the clinical researchers in serving minority populations, especially African-American and rural, geriatric and pediatric populations.