CONSORTIUM FOR THE LONGITUDINAL EVALUATION OF AFRICAN AMERICANS WITH EA (CLEAR)

与 EA 一起对非裔美国人进行纵向评估的联盟（CLEAR）

• 批准号: 7380405
• 负责人: LARRY W MORELAND
• 金额: $ 1.57万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-03-01 至 2007-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7380405
• 关键词: CONSORTIUM; LONGITUDINAL; EVALUATION; AFRICAN; AMERICANS

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to create a registry of African Americans with early rheumatoid arthritis. This is the first early rheumatoid arthritis registry in which a large cohort of African Americans is systematically studied in a longitudinal fashion. The registry will include a total of 500 patients who will be evaluable at 5 years disease duration. To obtain the goal of 500, as many as 600 patients will be enrolled. One of the primary aims of the registry is to isolate and immortalize genomic DNA from patient blood samples for use in future studies. The Pittman GCRC processes, stores, and isolates all genomic DNA obtained through this registry. The GCRC Informatics Core serves as the database repository using Teleform and other data management capabilities to manage the registry data. A total of 9 patients were enrolled in the reporting period, during which exemption status was pending from the OMB.

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这项研究的目的是建立一个登记的非洲裔美国人与早期类风湿关节炎。这是第一个早期类风湿性关节炎登记，其中一个大的队列非洲裔美国人是系统地研究了纵向的方式。该登记研究将纳入总计500例患者，这些患者将在5年疾病持续时间时进行评价。为了达到500例的目标，将招募多达600例患者。该注册的主要目的之一是从患者血液样本中分离和永生化基因组DNA，以用于未来的研究。Pittman GCRC处理、储存和分离通过该登记获得的所有基因组DNA。GCRC信息学核心作为数据库储存库，使用Teleform和其他数据管理功能管理登记册数据。本报告期间共入组9例患者，在此期间，OMB的豁免状态待定。